Beni C, Caylà J A, Jansà J M, Maldonado R, Pañella H, Rajmil L, Villalbí J R
Institut Universitari de Salut Pública de Catalunya.
Med Clin (Barc). 1999 Jan 16;112(1):1-4.
The purpose of the study is to estimate the incidence of Haemophilus influenzae type b invasive disease (HibID) and meningococcal disease (MD) in Barcelona (Catalonia, Spain) for the years 1994-1995.
Data were obtained from the nominal registry of the surveillance system for reportable transmissible diseases of the Barcelona City Health Department, combining the reporting system with active surveillance, including microbiological reports and the review of hospital discharge registries to ensure completeness.
During this two-years period there were 17 cases of HibID (12 meningitis), and for 12 cases there was a laboratory confirmation. The annual incidence rate can be estimated at 15.4 cases of HibID for 100,000 children below 5 years of age, and 4.5 cases for 100,000 children below 15 years. The annual incidence rates for Hib meningitis were 3.2 for 100,000 below 15 years. There were 60 cases of MD, and for 33 there was a laboratory confirmation, with a majority of serogroup B. The annual incidence rate of MD can be estimated at 32.6 cases for 100,000 below 5 years and 16 cases for 100,000 below 15 years. The incidence rate of meningococcal meningitis is at least 5.9 cases for 100,000 below 15 years of age.
These results confirm the relatively low incidence of Hib meningitis in Barcelona, Spain, while the Hib vaccine was not in systematic use, much lower than the incidence of MD. The incidence rates are similar to all other population-based studies in Spain, except for the Basque Country study.
本研究旨在估算1994 - 1995年巴塞罗那(西班牙加泰罗尼亚)b型流感嗜血杆菌侵袭性疾病(HibID)和脑膜炎球菌病(MD)的发病率。
数据取自巴塞罗那市卫生局法定传染病监测系统的名义登记处,将报告系统与主动监测相结合,包括微生物报告以及对医院出院登记处的审查以确保完整性。
在这两年期间,有17例HibID(12例脑膜炎),其中12例有实验室确诊。5岁以下儿童中HibID的年发病率估计为每10万人中有15.4例,15岁以下儿童为每10万人中有4.5例。15岁以下儿童中Hib脑膜炎的年发病率为每10万人中有3.2例。有60例MD,其中33例有实验室确诊,大多数为B血清群。MD的年发病率估计为5岁以下儿童每10万人中有32.6例,15岁以下儿童每10万人中有16例。15岁以下儿童中脑膜炎球菌性脑膜炎的发病率至少为每10万人中有5.9例。
这些结果证实,在西班牙巴塞罗那,Hib脑膜炎的发病率相对较低,当时Hib疫苗尚未系统使用,远低于MD的发病率。发病率与西班牙所有其他基于人群的研究相似,但巴斯克地区的研究除外。