双丁香酚在氧化锌丁香酚水门汀中的应用。
Application of bis-eugenol to a zinc oxide eugenol cement.
作者信息
Fujisawa S, Kashiwagi Y, Atsumi T, Iwakura I, Ueha T, Hibino Y, Yokoe I
机构信息
Department of Oral Diagnosis, Meikai University, School of Dentistry, Saitama-ken, Japan.
出版信息
J Dent. 1999 May;27(4):291-5. doi: 10.1016/s0300-5712(98)00056-6.
OBJECTIVES
To assess the usefulness of dimerized eugenol (bis-eugenol) in dentistry, the physical properties of zinc oxide eugenol cement (ZOE) with bis-eugenol and the cytotoxicity of bis-eugenol were studied.
METHODS
Setting time, compressive strength, solubility and disintegration of ZOE cement with bis-eugenol according to the specifications of JDMAS315 were evaluated. The cytotoxicity of bis-eugenol and eugenol toward two different cell types, HGF (a primary culture of human gingival fibroblast) and HSG (a human epidermoid carcinoma cell line derived from a salivary gland) was evaluated by the MTT test and in terms of cell survival.
RESULTS
Addition of bis-eugenol to ZOE did not decrease the physical properties when employed at the ratio of 9:1 or 6:1 (liquid ND:bis-eugenol, w/w). Bis-eugenol was less toxic than eugenol in the cell culture tests.
CONCLUSIONS
The results of this assay demonstrated that bis-eugenol is useful in ZOE.
目的
为评估二聚丁香酚（双丁香酚）在牙科领域的效用，对含双丁香酚的氧化锌丁香酚水门汀（ZOE）的物理性能及双丁香酚的细胞毒性进行了研究。
方法
根据日本牙科材料规格标准JDMAS315评估含双丁香酚的ZOE水门汀的凝固时间、抗压强度、溶解度和崩解情况。通过MTT试验并依据细胞存活率评估双丁香酚和丁香酚对两种不同细胞类型，即人牙龈成纤维细胞原代培养物（HGF）和源自唾液腺的人表皮样癌细胞系（HSG）的细胞毒性。
结果
当以9:1或6:1的比例（液体ND：双丁香酚，重量/重量）使用时，向ZOE中添加双丁香酚不会降低其物理性能。在细胞培养试验中，双丁香酚的毒性低于丁香酚。
结论
该试验结果表明双丁香酚在ZOE中有用。
Zotero 插件