牛皮癣素（S100A7）：一种用于膀胱鳞状细胞癌患者随访的潜在尿液标志物。
Psoriasin (S100A7): a putative urinary marker for the follow-up of patients with bladder squamous cell carcinomas.
作者信息
Ostergaard M, Wolf H, Orntoft T F, Celis J E
机构信息
Department of Medical Biochemistry and Danish Centre for Human Genome Research, University of Aarhus, Aarhus C.
出版信息
Electrophoresis. 1999 Feb;20(2):349-54. doi: 10.1002/(SICI)1522-2683(19990201)20:2<349::AID-ELPS349>3.0.CO;2-B.
To search for bladder squamous cell carcinoma markers that are released to the urine a blind and systematic analysis of the protein profiles of fresh tumors, their secreted proteins, as well as the patient's urine was carried out using state-of-the-art proteomic technology. We review the data concerning the putative marker psoriasin (S100A7), which, alone or in combination with other biomarkers, may be valuable for the noninvasive follow-up of patients bearing these tumors.
为了寻找释放到尿液中的膀胱鳞状细胞癌标志物，我们使用最先进的蛋白质组学技术，对新鲜肿瘤的蛋白质谱、其分泌的蛋白质以及患者尿液进行了盲法和系统的分析。我们回顾了有关假定标志物银屑素（S100A7）的数据，该标志物单独或与其他生物标志物联合使用，可能对这些肿瘤患者的无创随访具有重要价值。
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