Zargar A H, Wani A I, Masoodi S R, Laway B A, Bashir M I
Department of Endocrinology, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, India.
Diabetes Res Clin Pract. 1999 Jan;43(1):67-74. doi: 10.1016/s0168-8227(98)00112-0.
This retrospective study presents the mortality trends in diabetic patients in a developing region of the world. The data were collected by screening the hospital records of all diabetic patients who died over a period of a decade at Institute of Medical Sciences, a tertiary care medical centre in Kashmir Valley of India. Of 133,374 patients admitted to the centre from January 1987 to December 1996, 9627 died, of whom 269 (151 males and 118 females) were recorded to have diabetes mellitus. The mean+/-S.D. age at the time of death was 51.61+/-13.77 years for males and 51.50+/-15.50 years for females. The common causes contributing to death were infections (33.83%), chronic renal failure (30.85%), coronary artery disease (16.36%), cerebrovascular disease (13.75%), hypoglycaemia (7.81%), diabetic ketoacidosis (6.69%) and hyperosmolar coma (2.23%). In 7.43% patients the cause of death could not be ascertained. Death was attributed to single cause in 60.22%, to two causes in 26.39% and to three or more causes in 5.95%. Most (59.11%) of these diabetic patients died within a week of hospitalisation. We conclude that mortality trends in diabetes mellitus differ in developing regions as compared to developed regions reflecting poor healthcare in general and diabetic care in particular. Unlike in west, where the major killers in diabetic patients are coronary artery disease and cerebrovascular disease, infections and chronic renal failure continue to be leading causes of death in patients with diabetes mellitus in developing regions like ours.
这项回顾性研究呈现了世界某发展中地区糖尿病患者的死亡率趋势。数据是通过筛查印度克什米尔山谷一家三级医疗中心——医学科学研究所十年间所有死亡糖尿病患者的医院记录收集而来。在1987年1月至1996年12月期间入住该中心的133374名患者中,9627人死亡,其中269人(151名男性和118名女性)被记录患有糖尿病。男性死亡时的平均±标准差年龄为51.61±13.77岁,女性为51.50±15.50岁。导致死亡的常见原因包括感染(33.83%)、慢性肾衰竭(30.85%)、冠状动脉疾病(16.36%)、脑血管疾病(13.75%)、低血糖(7.81%)、糖尿病酮症酸中毒(6.69%)和高渗性昏迷(2.23%)。7.43%的患者死亡原因无法确定。60.22%的患者死亡归因于单一原因,26.39%归因于两种原因,5.95%归因于三种或更多原因。这些糖尿病患者大多数(59.11%)在住院一周内死亡。我们得出结论,与发达地区相比,发展中地区糖尿病的死亡率趋势有所不同,这反映出总体医疗保健水平较差,尤其是糖尿病护理水平。与西方不同,在西方糖尿病患者的主要死因是冠状动脉疾病和脑血管疾病,而在我们这样的发展中地区,感染和慢性肾衰竭仍然是糖尿病患者死亡的主要原因。