卵巢间质型莱迪希细胞瘤。病例报告及文献综述。

Stromal Leydig cell tumor of the ovary. Case report and literature review.

作者信息

Takeuchi S, Ishihara N, Ohbayashi C, Itoh H, Maruo T

机构信息

Department of Obstetrics and Gynecology, Kobe University School of Medicine, Japan.

出版信息

Int J Gynecol Pathol. 1999 Apr;18(2):178-82. doi: 10.1097/00004347-199904000-00014.

DOI:10.1097/00004347-199904000-00014

PMID:10202678

Abstract

The stromal Leydig cell tumor is a very rare benign tumor originating from the ovarian stroma. Only seven cases have been reported, all in postmenopausal women, except for one in a 15-year-old girl. In the present case, masculinization developed over a few months in a 24-year-old woman. The serum concentration of testosterone was 4.7 ng/ml before operation. Left salpingo-oophorectomy and wedge resection of the right ovary were performed. The encapsulated left ovarian tumor was an ovarian stromal Leydig cell tumor on microscopic examination.

摘要

间质型莱迪希细胞瘤是一种非常罕见的起源于卵巢间质的良性肿瘤。仅报道过7例，除1例为15岁女孩外，其余均为绝经后女性。在本病例中，一名24岁女性在几个月内出现男性化表现。术前血清睾酮浓度为4.7 ng/ml。实施了左侧输卵管卵巢切除术和右侧卵巢楔形切除术。经显微镜检查，包膜完整的左侧卵巢肿瘤为卵巢间质型莱迪希细胞瘤。