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对于晚期头颈癌,综合治疗后进行常规随访是否有用?

Is routine follow-up useful after combined-modality therapy for advanced head and neck cancer?

作者信息

Cooney T R, Poulsen M G

机构信息

Department of Otolaryngology/Head and Neck Surgery, Princess Alexandra Hospital, Brisbane, Queensland, Australia.

出版信息

Arch Otolaryngol Head Neck Surg. 1999 Apr;125(4):379-82. doi: 10.1001/archotol.125.4.379.

Abstract

OBJECTIVE

To evaluate the usefulness of routine follow-up in a selected group of patients with head and neck cancer.

DESIGN

Retrospective cohort study with follow-up of 5 years for all patients.

PATIENTS

Three hundred two patients with advanced (stage II or IV) squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx, and larynx were treated with curative intent with surgery and postoperative radiation therapy between January 1, 1970, and December 31, 1990.

MAIN OUTCOME MEASURE

Survival after recurrence of the index tumor or the development of a second head and neck primary tumor.

RESULTS

Overall actuarial 5-year survival was 56%. Relapse occurred in 119 patients, and salvage therapy was attempted in 49 patients. Only 2 patients survived to 5 years after relapse.

CONCLUSION

In patients with advanced head and neck squamous cell carcinoma, routine follow-up is more important for evaluation of treatment results and emotional support than of benefit in improving patient survival.

摘要

目的

评估对头颈部癌特定患者群体进行常规随访的实用性。

设计

对所有患者进行5年随访的回顾性队列研究。

患者

1970年1月1日至1990年12月31日期间,302例患有晚期(II期或IV期)口腔、口咽、下咽和喉鳞状细胞癌的患者接受了根治性手术及术后放射治疗。

主要观察指标

原发肿瘤复发或出现第二个头颈部原发性肿瘤后的生存率。

结果

总体精算5年生存率为56%。119例患者出现复发,49例患者尝试了挽救性治疗。复发后仅有2例患者存活至5年。

结论

对于晚期头颈部鳞状细胞癌患者,常规随访在评估治疗效果和给予情感支持方面比改善患者生存率更重要。

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