Gullino D, Giordano O, Lijoi C, Masella M, De Carlo A
Divisione di Chirurgia Generale, USL n. 17, Regione Piemonte, Ospedale SS. Annunziata, Savigliano, Cuneo.
Minerva Chir. 1998 Dec;53(12):1059-67.
The incidence of perforative diverticulitis of the left colon is steadily increasing. Today the decision is generally taken to perform two-stage surgery: segmentary resection without (Hartmann's operation) or with anastomosis, but protected by a colostomy ("limited intervention"). This study aimed to examine standard colectomy performed in a single operation ("ideal intervention").
Left colectomy with primary ligature of the lower mesenteric artery and vein at the source and outlet, en bloc removal of the colon-mesocolon and immediate transverse colorectal anastomosis. Anastomosis protected by the omentum which is also used to peritonise the retroperitoneum and to wrap around the anastomosis, and anastomosis also protected by the author's three-way lavage and active aspiration tube in either a trans- or subanastomosis and transanal position. Urgency is essential for this single-stage operation, together with massive dose antibiotic treatment limited to the pre- and postoperative stages, but above all peritoneal cleansing using accurate, methodical, repeated and abundant lavage with 8-10-20 or more litres, but only used 500 ml at a time. Of these 65 cases, 40 (62%) were purulent localised peritonitis and 25 (38%) were generalised (14 purulent, 4 fecaloid and 7 fecal). 8 cases (12.3%) underwent surgery in three stages and 16 (24.6%) underwent sigmoidectomy in one or two stages ("limited intervention"), 41 cases (63%) (1985-95, when Gullino's three-way tube became available) underwent standard colectomy in a single stage.
Morbidity in 10 cases/65 (15%) and septic mortality in 5 cases/65 (7.7%) (limited to generalised peritonitis alone) only affected patients undergoing "limited interventions", but none of the 41 patients undergoing "ideal intervention". Mortality was significantly influenced by age: 50% of over 80 year-olds, none below 60. Postoperative hospitalisation was 17.1 days (in the first stage) of "limited interventions" and 9.7 days for "ideal interventions".
The results argue clearly in favour of the "courageous" ideal colectomy with peritoneal lavage and protection of the colorectal anastomosis using Gullino's three-way tube.
左半结肠穿孔性憩室炎的发病率正在稳步上升。如今,一般决定采用两阶段手术:不进行吻合(哈特曼手术)或进行吻合的节段性切除,但需行结肠造口术保护(“有限干预”)。本研究旨在探讨单次手术完成的标准结肠切除术(“理想干预”)。
在源头和出口处对肠系膜下动静脉进行一级结扎的左半结肠切除术,整块切除结肠 - 结肠系膜,并立即进行横结肠直肠吻合。用大网膜保护吻合口,大网膜还用于覆盖腹膜后间隙并包裹吻合口,同时在吻合口上方或下方以及经肛门位置放置作者的三腔冲洗和主动吸引管保护吻合口。对于这种单阶段手术,紧迫性至关重要,同时大剂量抗生素治疗仅限于术前和术后阶段,但最重要的是进行准确、系统、反复且大量的冲洗以清洁腹膜,冲洗量为8 - 10 - 20升或更多,但每次仅使用500毫升。在这65例病例中,40例(62%)为脓性局限性腹膜炎,25例(38%)为弥漫性腹膜炎(14例脓性、4例粪性和7例粪样)。8例(12.3%)分三个阶段进行手术,16例(24.6%)进行一或两个阶段的乙状结肠切除术(“有限干预”),41例(63%)(1985 - 1995年,当时古利诺三腔管可用)进行单阶段标准结肠切除术。
10例/65例(15%)出现并发症,5例/65例(7.7%)发生感染性死亡(仅限于弥漫性腹膜炎),仅影响接受“有限干预”的患者,但41例接受“理想干预”的患者均未出现。死亡率受年龄影响显著:80岁以上患者中有50%死亡;60岁以下患者无死亡。“有限干预”的术后住院时间为17.1天(第一阶段),“理想干预”为9.7天。
结果明确支持采用腹膜冲洗并使用古利诺三腔管保护结肠直肠吻合口的“大胆”理想结肠切除术。