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Structure and validation of a pharmacokinetic model for benzene.

作者信息

Sinclair G C, Gray C N, Sherwood R J

机构信息

Occupational Hygiene Unit, Deakin University, Victoria, Australia.

出版信息

Am Ind Hyg Assoc J. 1999 Mar-Apr;60(2):249-58. doi: 10.1080/00028899908984444.

Abstract

A pharmacokinetic model for benzene has been developed and validated for the inhalation aspects of its operation. The validation shows reasonable agreement between the model outputs and human biological data for phenol in urine, benzene in alveolar air, and benzene in mixed exhaled air.

摘要

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