Piccolo R, Lipman J, Hon H, Burrows R C
Department of Anaesthesia, Baragwanath Hospital, Johannesburg.
S Afr J Surg. 1999 Feb;37(1):15-20.
Advancements in intensive care therapy have progressed rapidly over the last two decades. Associated with this have been scientifically unsubstantiated sedation and analgesia practices in the intensive care unit. There is little consensus as to which agents are the most suitable, let alone when and how to use them. There are few, if any, placebo-controlled trials involving sedative drugs in critically ill patients. In an analysis of the literature, we have attempted to present a practical approach to sedation and analgesia practices in the critically ill patient. The aim is to present a framework upon which medical personnel managing critically ill patients can develop a strategy for their own circumstances.
在过去二十年中，重症监护治疗取得了迅速进展。与此相关的是，重症监护病房中存在一些未经科学证实的镇静和镇痛做法。对于哪种药物最合适，更不用说何时以及如何使用这些药物，几乎没有共识。涉及危重病患者使用镇静药物的安慰剂对照试验极少（如果有的话）。在对文献的分析中，我们试图提出一种针对危重病患者镇静和镇痛做法的实用方法。目的是提供一个框架，供管理危重病患者的医务人员根据自身情况制定策略。
