Must A, Strauss R S
Department of Family Medicine and Community Health, Tufts University School of Medicine, Boston, MA 02111, USA.
Int J Obes Relat Metab Disord. 1999 Mar;23 Suppl 2:S2-11. doi: 10.1038/sj.ijo.0800852.
This report reviews the risks and consequences associated with childhood and adolescent obesity. Although no consensus definition of childhood obesity exists, the various measures encountered in the literature are moderately well correlated. The paper is organized in three parts. The first section reviews childhood obesity sequelae that occur during childhood. These short-term risks, for orthopedic, neurological, pulmonary, gasteroenterological, and endocrine conditions, although largely limited to severely overweight children, are becoming more common as the prevalence of severe overweight rises. The social burden of pediatric obesity, especially during middle childhood and adolescence, may have lasting effects on self-esteem, body image and economic mobility. The second section examines the intermediate consequences, such as the development of cardiovascular risk factors and persistence of obesity into adulthood. These mid-range effects of early obesity presage later adult disease and premature mortality. In the final section, the small body of research on the long-term morbidity and mortality associated with childhood obesity is reviewed. These studies suggest that risk of cardiovascular disease and all-cause mortality is elevated among those who were overweight during childhood. The high prevalence and dramatic secular trend toward increasing childhood obesity suggest that without aggressive approaches to prevention and treatment, the attendant health and social consequences will be both substantial and long-lasting.
本报告回顾了与儿童及青少年肥胖相关的风险和后果。尽管目前尚无关于儿童肥胖的共识性定义,但文献中所提及的各种测量方法之间存在适度的良好相关性。本文分为三个部分。第一部分回顾了儿童期出现的儿童肥胖后遗症。这些短期风险涉及骨科、神经科、肺部、胃肠科和内分泌疾病,虽然主要局限于严重超重的儿童,但随着严重超重患病率的上升,正变得越来越普遍。儿童肥胖的社会负担,尤其是在童年中期和青春期,可能会对自尊、身体形象和经济流动性产生持久影响。第二部分探讨了中期后果,如心血管危险因素的发展以及肥胖持续至成年期。早期肥胖的这些中期影响预示着成年后期的疾病和过早死亡。在最后一部分,回顾了关于儿童肥胖相关的长期发病率和死亡率的少量研究。这些研究表明,童年时期超重的人群患心血管疾病和全因死亡率的风险会升高。儿童肥胖的高患病率以及明显的长期上升趋势表明,如果不采取积极的预防和治疗措施,随之而来的健康和社会后果将是巨大且持久的。