González-López A, Velasco E, Pozo T, Del Villar A
Departments of Dermatology, Río Hortega University Hospital, Valladolid, Spain.
Br J Dermatol. 1999 May;140(5):931-4. doi: 10.1046/j.1365-2133.1999.02829.x.
HIV-associated pityriasis rubra pilaris (PRP) or PRP type VI designates a new distinctive entity reported in HIV patients. It is characterized by cutaneous lesions of PRP and variable association with lesions of acne conglobata, hidradenitis suppurativa and lichen spinulosus. We report a patient with HIV-associated PRP which was treated by triple antiretroviral therapy (zidovudine, lamivudin and saquinavir) with complete response. The patient has remained free from symptoms for 20 months of follow-up. We review the clinical features, pathology, evolution, treatment and possible aetiology of this recently described entity.
人类免疫缺陷病毒(HIV)相关的毛发红糠疹(PRP)或VI型PRP指的是在HIV患者中报告的一种新的独特病症。其特征为PRP皮肤损害,并与聚合性痤疮、化脓性汗腺炎及棘状苔藓损害存在不同程度的关联。我们报告了一名接受三联抗逆转录病毒疗法(齐多夫定、拉米夫定和沙奎那韦)治疗且获得完全缓解的HIV相关PRP患者。该患者在20个月的随访期内一直无症状。我们对这一最近描述的病症的临床特征、病理、演变、治疗及可能的病因进行了综述。