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改良布莱洛克-陶西格分流术会导致对侧肺动脉生长吗?

Does the modified Blalock-Taussig shunt cause growth of the contralateral pulmonary artery?

作者信息

Jahangiri M, Lincoln C, Shinebourne E A

机构信息

Department of Cardiothoracic Surgery, Royal Brompton Hospital, London, England.

出版信息

Ann Thorac Surg. 1999 May;67(5):1397-9. doi: 10.1016/s0003-4975(99)00144-7.

Abstract

BACKGROUND

Although some pediatric cardiology departments have a policy of adopting primary correction of tetralogy of Fallot in all symptomatic infants, we and others still palliate neonates and infants. Effective palliation should ameliorate symptoms and allow growth of the pulmonary arteries. Although studies on the growth of the ipsilateral and contralateral pulmonary arteries after a classic Blalock-Taussig shunt have been reported, pulmonary artery growth after a modified Blalock-Taussig shunt has not been studied as thoroughly. Therefore, we examined whether there is equal growth of the contralateral pulmonary artery after a modified Blalock-Taussig shunt.

METHODS

We retrospectively analyzed the records of 140 patients with symptomatic tetralogy of Fallot who had a modified Blalock-Taussig shunt between October 1985 and October 1995. The median age at the time of the Blalock-Taussig shunt was 1.6 months. All patients had corrective procedures at a median age of 1.7 years. Cineangiography was done before the corrective procedure. From the angiograms the diameter of the right and left pulmonary arteries before their first lobar branches and the diameter of the descending thoracic aorta at the level of the diaphragm were measured. For each patient the ratios of right pulmonary artery to descending thoracic aorta and left pulmonary artery to descending thoracic aorta were determined and compared using Student's t test.

RESULTS

Of the 140 patients, 114 had a left-sided Blalock-Taussig shunt, 20 had a right-sided shunt, and 6 patients had bilateral shunts. The mean right pulmonary artery to descending thoracic aorta ratio was 1.10 and the mean left pulmonary artery to descending thoracic aorta ratio was 0.98. This difference was not significant.

CONCLUSION

We showed equal growth of the right and left pulmonary arteries with no distortion after a modified Blalock-Taussig shunt. If palliation is considered, the modified Blalock-Taussig shunt remains our choice.

摘要

背景

尽管一些儿科心脏病学部门制定了对所有有症状婴儿采用法洛四联症一期矫治的政策,但我们和其他一些机构仍对新生儿和婴儿进行姑息治疗。有效的姑息治疗应能缓解症状并促进肺动脉生长。虽然已有关于经典布莱洛克 - 陶西格分流术后同侧和对侧肺动脉生长的研究报道,但改良布莱洛克 - 陶西格分流术后的肺动脉生长尚未得到充分研究。因此,我们研究了改良布莱洛克 - 陶西格分流术后对侧肺动脉是否有同等程度的生长。

方法

我们回顾性分析了1985年10月至1995年10月期间140例有症状的法洛四联症患者的记录,这些患者接受了改良布莱洛克 - 陶西格分流术。布莱洛克 - 陶西格分流术时的中位年龄为1.6个月。所有患者在中位年龄1.7岁时接受了矫治手术。在矫治手术前进行了心血管造影。从血管造影中测量左右肺动脉在其第一级叶分支之前的直径以及膈肌水平的降主动脉直径。对于每位患者,确定右肺动脉与降主动脉的比值以及左肺动脉与降主动脉的比值,并使用学生t检验进行比较。

结果

140例患者中,114例行左侧布莱洛克 - 陶西格分流术,20例行右侧分流术,6例患者行双侧分流术。右肺动脉与降主动脉的平均比值为1.10,左肺动脉与降主动脉的平均比值为0.98。这种差异不显著。

结论

我们发现改良布莱洛克 - 陶西格分流术后左右肺动脉生长程度相同且无扭曲。如果考虑进行姑息治疗,改良布莱洛克 - 陶西格分流术仍是我们的选择。

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