Robert M, Rakotomalala E, Delbos O, Navratil H
Department of Urology, Lapeyronie University Hospital, Montpellier, France.
J Endourol. 1999 Apr;13(3):157-60. doi: 10.1089/end.1999.13.157.
The aim of this randomized study was to assess the relation between shockwave frequency, sedation, and efficiency in piezoelectric extracorporeal shockwave lithotripsy (SWL) for ureteral calculi.
A random sample of 114 patients aged between 15 and 74 (mean 45) years were treated at the shockwave frequencies of 1 (N = 57) or 4 (N = 57) per second using the EDAP LT 02 lithotripter at maximum energy. The stones' largest diameter ranged from 5 to 18 mm (mean 7.6 mm). Lower ureteral stones were treated with the patient in the prone position and upper ureteral stones in supine position. The duration of SWL sessions and stone measurements were statistically similar for patients treated at low and high frequencies. The levels of required sedation (none, intramuscular analgesia, intravenous sedation-analgesia) and stone-free rates after one session were analyzed by Student's t-test or Fisher's exact test.
Sedation did not differ statistically with SWL frequency for mid and lower ureteral calculi. However, the use of intravenous sedation-analgesia was less common for patients with upper ureteral stones treated at low rather than high frequency (19% and 100%, respectively; P < 0.0001). The success rate was significantly lower (P = 0.04) for lower ureteral calculi treated at low v high frequency (65 % and 89%, respectively) but was not statistically affected by frequency for upper ureteral stones.
We recommend high frequency for piezoelectric SWL of lower ureteral calculi, especially for stones with a maximum diameter > or =8 mm. On the other hand, low-frequency SWL appears to be suitable for the treatment of upper ureteral stones.
本随机研究旨在评估冲击波频率、镇静与压电式体外冲击波碎石术(SWL)治疗输尿管结石的效率之间的关系。
随机抽取114例年龄在15至74岁(平均45岁)之间的患者,使用EDAP LT 02碎石机以每秒1次(N = 57)或4次(N = 57)的冲击波频率,以最大能量进行治疗。结石最大直径范围为5至18毫米(平均7.6毫米)。治疗下段输尿管结石时患者取俯卧位,治疗上段输尿管结石时患者取仰卧位。低频和高频治疗患者的SWL疗程持续时间和结石测量数据在统计学上相似。通过学生t检验或费舍尔精确检验分析所需镇静水平(无、肌肉注射镇痛、静脉镇静镇痛)和单次治疗后的结石清除率。
对于中段和下段输尿管结石,镇静与SWL频率在统计学上无差异。然而,对于上段输尿管结石,低频治疗的患者使用静脉镇静镇痛的情况比高频治疗的患者少见(分别为19%和100%;P < 0.0001)。下段输尿管结石低频治疗的成功率显著低于高频治疗(分别为65%和89%,P = 0.04),但上段输尿管结石的成功率不受频率的统计学影响。
我们建议对下段输尿管结石进行压电式SWL时采用高频,特别是对于最大直径≥8毫米的结石。另一方面,低频SWL似乎适用于上段输尿管结石的治疗。