D'Souza R M, Watson C, Kennett M
National Centre for Epidemiology and Population Health, Australian National University, Australian Capital Territory. Rennie.D'
Aust N Z J Public Health. 1999 Jun;23(3):289-94. doi: 10.1111/j.1467-842x.1999.tb01258.x.
To provide evidence according to the requirements of the Global Commission for Certification of Poliomyelitis Eradication that poliomyelitis has been eliminated in Australia.
Documentation of the surveillance of poliomyelitis, the presence of a comprehensive national immunisation program, and a network of laboratories for viral diagnosis. Active surveillance of acute flaccid paralysis (AFP) cases was initiated in 1995 to prove that poliovirus does not cause such paralysis. Australia is also evaluating the surveillance of AFP through a retrospective hospital based study.
The last case in Australia of polio due to wild poliovirus was seen in 1978 and the last case of vaccine-associated paralytic poliomyelitis detected by serology was in 1994. The latest immunisation coverage figures for OPV3 for children under one year of age is 85.6%. The Australian National Polio Reference Laboratory has tested 821 enteroviruses since 1994 and have not identified any wild poliovirus. The average rate of non-polio AFP based on 111 cases investigated for the period 1995-98 is 0.71 per 100,000 under the age of 15 years. Stool samples were collected from only 21% of cases.
The process of certification of the eradication of poliomyelitis in Australia is almost complete. Although immunisation coverage is high, improvement in AFP surveillance and stool collection is vital for the certification process. The next challenge is the containment of polioviruses.
Although Australia and other Western Pacific countries are likely to be certified as wild-polio free in 2000, a comprehensive immunisation program and surveillance must continue for three years after global certification (expected 2003-04).
根据全球根除脊髓灰质炎认证委员会的要求,提供澳大利亚已根除脊髓灰质炎的证据。
记录脊髓灰质炎监测情况、全面的国家免疫规划的存在以及病毒诊断实验室网络。1995年开始对急性弛缓性麻痹(AFP)病例进行主动监测,以证明脊髓灰质炎病毒不会导致此类麻痹。澳大利亚还通过一项基于医院的回顾性研究评估AFP监测情况。
澳大利亚最后一例由野生脊髓灰质炎病毒引起的脊髓灰质炎病例出现在1978年,通过血清学检测到的最后一例疫苗相关麻痹性脊髓灰质炎病例是在1994年。一岁以下儿童OPV3的最新免疫覆盖率为85.6%。自1994年以来,澳大利亚国家脊髓灰质炎参考实验室已检测了821株肠道病毒,未发现任何野生脊髓灰质炎病毒。基于1995 - 1998年期间调查的111例病例,15岁以下儿童非脊髓灰质炎AFP的平均发病率为每10万人0.71例。仅21%的病例采集了粪便样本。
澳大利亚根除脊髓灰质炎的认证过程已基本完成。尽管免疫覆盖率很高,但改善AFP监测和粪便采集对于认证过程至关重要。下一个挑战是控制脊髓灰质炎病毒。
尽管澳大利亚和其他西太平洋国家可能在2000年被认证为无野生脊髓灰质炎,但在全球认证(预计2003 - 2004年)后的三年里,必须继续实施全面的免疫规划和监测。