Persistent activation of calcium-activated and calcium-independent protein kinase C in response to electrical afterdischarge from peptidergic neurons of aplysia.
作者信息
Wayne N L, Lee W, Kim Y J
机构信息
Department of Physiology, UCLA School of Medicine, Room 53-231 CHS, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA.
出版信息
Brain Res. 1999 Jul 10;834(1-2):211-3. doi: 10.1016/s0006-8993(99)01594-2.
Abstract
The purpose of this work was to investigate the effects of electrical afterdischarge on protein kinase C (PKC) activity from bag cell neurons (BCNs) of Aplysia. Bilateral clusters of BCNs were divided: one cluster was stimulated to afterdischarge, the other was a control. Clusters were processed for PKC activity assay 5-120 min after electrical stimulation. Afterdischarge triggered a rapid and persistent increase in both calcium-activated and calcium-independent PKC activity.
摘要
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