Druschky K, Stefan H, Grehl H, Neundörfer B
Neurologische Klinik, Friedrich-Alexander-Universität Erlangen-Nürnberg.
Nervenarzt. 1999 Jun;70(6):556-9. doi: 10.1007/s001150050480.
We report about a 57-year-old patient suffering from the typical symptoms of normal-pressure hydrocephalus (NPH) including gait disturbance, urinary incontinence, and mental deterioration. CSF analysis established the diagnosis of chronic active Lyme neuroborreliosis with lymphocytic pleocytosis and intrathecal Borrelia burgdorferi antibody production. After several weeks of i.v. antibiotic treatment we observed normalization of CSF parameters as well as a clear improvement of clinical symptoms so that surgical shunting was no longer indicated. Interference with subarachnoid CSF flow may be a possible cause of the observed symptomatic NPH in a patient with chronic Lyme neuroborreliosis.
我们报告了一名57岁的患者,其患有正常压力脑积水(NPH)的典型症状,包括步态障碍、尿失禁和精神衰退。脑脊液分析确诊为慢性活动性莱姆神经疏螺旋体病,伴有淋巴细胞增多和鞘内伯氏疏螺旋体抗体产生。经过数周的静脉抗生素治疗后,我们观察到脑脊液参数恢复正常,临床症状也明显改善,因此不再需要进行手术分流。对于一名患有慢性莱姆神经疏螺旋体病的患者,蛛网膜下腔脑脊液流动受到干扰可能是观察到的症状性NPH的一个可能原因。