Pérez García F J, Regadera Sejas F J, Rodríguez Martínez J J, Martínez Gómez F J, Casasola Chamorro J, Sánchez Trilla A
Servicio de Urología I, Hospital Covadonga, Oviedo, Asturias, España.
Arch Esp Urol. 1999 Jun;52(5):471-7.
To present our experience with synchronous bilateral renal adenocarcinoma. The indications for conservative surgery, the different types and the controversies are discussed.
5 patients with bilateral renal adenocarcinoma from our series of 320 renal adenocarcinomas were analyzed for gender, age at presentation, tumor location, size, presenting features and type of surgery performed.
Bilateral renal adenocarcinoma accounted for 1.56% in our series. Mean age at presentation was 57.8 years (range 43-69 years). All 5 patients were male. All patients underwent conservative surgery by tumor excision or partial nephrectomy of the side with less involvement followed by delayed radical surgery of the contralateral side. Follow-up ranged from 19 months to 14 years. To date all patients are disease-free and only one is on dialysis 14 years postoperatively.
Bilateral renal adenocarcinoma has been reported to account for 1.4%-5% of all renal masses. The incidence in our series was 1.56%. Conservative renal surgery is indicated in patients like those described herein to prevent the need for dialysis. In our view, conservative renal surgery is a good therapeutic option that carries a small risk of tumor multicentricity and future recurrence.
介绍我们在同步双侧肾腺癌方面的经验。讨论保守手术的指征、不同类型及争议点。
对我们320例肾腺癌系列中的5例双侧肾腺癌患者进行分析,内容包括性别、就诊时年龄、肿瘤位置、大小、临床表现及所施行的手术类型。
双侧肾腺癌在我们的系列中占1.56%。就诊时平均年龄为57.8岁(范围43 - 69岁)。所有5例患者均为男性。所有患者均先对受累较轻一侧行肿瘤切除或部分肾切除术进行保守手术,随后对侧行延迟性根治性手术。随访时间为19个月至14年。迄今为止,所有患者均无疾病,仅1例在术后14年需要透析。
据报道,双侧肾腺癌占所有肾肿块的1.4% - 5%。我们系列中的发病率为1.56%。对于本文所述类型的患者,行保守性肾手术可避免透析的需要。我们认为,保守性肾手术是一种良好的治疗选择,肿瘤多中心性及未来复发风险较小。