Pariselle J, Froussart F, Sarrazin J L, Bidaux F, Rigal Sastourne J C, May F, Renard J P, Maurin J F
Service d'Ophtalmologie et d'Imagerie Médicale, HIA Du Val-de-Grâce 74, Paris.
J Fr Ophtalmol. 1999 Jun-Jul;22(6):628-34.
To evaluate a new magnetic resonance imaging protocol for dynamic study of the lacrimal outflow system and to use this protocol to search for problems in patients with an assumed permeable outflow system who develop epiphora.
A prospective study of nine patients, including 2 asymptomatic controls was conducted. The magnetic resonance protocol included, gadolinium instillation into the conjunctival cul-de-sac, 3D gradient-echo T1-weighted acquisition, 2 mm thick images passing through the nasolacrimal duct, dynamic acquisition after gadolinium instillation for timing dye progression through the outflow system.
Similar results were obtained for the two control subjects with lacrimal transit time of a median 100 seconds. Three distinct events were individualized gadolinium arrival in the lacrimal sac (t1), at the extremity of the bony portion of the lacrimal duct (té), and the extremity of the mucosal portion of the duct (t3). Patients with an assumed permeable outflow system who had epiphora show results intermediary between passed dye and total blockage of the dye within the lacrimal sac.
The study of the lacrimal outflow system using this new magnetic resonance imaging protocol contributes to the physiological study of tear evacuation and could be useful for quantitative assessment of lacrimal stenosis, particularly interesting for therapeutic guidance.
评估一种用于泪液流出系统动态研究的新磁共振成像方案,并使用该方案寻找假定泪液流出系统通畅但出现溢泪的患者的问题。
对9名患者进行了前瞻性研究,其中包括2名无症状对照者。磁共振成像方案包括:将钆剂滴入结膜穹窿,进行三维梯度回波T1加权采集,获取2毫米厚的穿过鼻泪管的图像,在滴入钆剂后进行动态采集以确定染料在流出系统中的进展时间。
两名对照者的泪液通过时间中位数为100秒,获得了相似的结果。钆剂到达泪囊(t1)、泪管骨性部分末端(té)和泪管黏膜部分末端(t3)这三个不同事件可被区分开来。假定泪液流出系统通畅但出现溢泪的患者的结果介于染料通过和泪囊内染料完全阻塞之间。
使用这种新的磁共振成像方案对泪液流出系统进行研究有助于泪液排出的生理学研究,并且可能对泪道狭窄的定量评估有用,对治疗指导尤其有意义。