Wong D T, Gomez M, McGuire G P, Kavanagh B
Department of Anesthesia, The Toronto Hospital, University of Toronto, Ontario, Canada.
Crit Care Med. 1999 Jul;27(7):1319-24. doi: 10.1097/00003246-199907000-00020.
To analyze the utilization of intensive care unit (ICU) days in a Canadian medical-surgical ICU and to identify ICU patients with prolonged ICU length of stay (LOS).
Prospective descriptive study.
A Canadian tertiary care medical-surgical ICU.
Consecutive patients admitted to an adult medical-surgical ICU. Neurosurgical, cardiac surgical, and coronary care unit patients were excluded.
For each ICU admission, patient demographics, diagnosis, Acute Physiology and Chronic Health Evaluation II (APACHE II) score, ICU LOS, and hospital mortality were collected. The patients' risk of death was calculated using the APACHE II equation. Admissions were stratified by ICU LOS into four groups: 1 to 2, 3 to 6, 7 to 13, and > or = 14 days. Among the four LOS groups, the number of ICU days and observed and predicted death rates were compared. Admissions were also stratified by risk of death into five probability range quintiles. Among the five risk groups, ICU LOS was compared between survivors and nonsurvivors.
A total of 1,960 admissions utilized 9,298 ICU days. ICU LOS (mean +/- SEM) was 4.74 +/- 0.2 (median, 2; range, 1 to 178) days. Short-stay patients (ICU LOS < or = 2 days) accounted for 60.3% of total admissions but consumed only 16.4% of total ICU days. Long-stay patients (ICU LOS > or = 14 days) accounted for 7.3% of total admissions but consumed 43.5% of total ICU days. Among the long-stay patients, the most common reasons for admission were pneumonia, multiple trauma, neuromuscular weakness, and septic shock. The mortality for long-stay patients approached 50%. When analyzed by patients' mortality risks, those with a risk of death >0.8 (predicted to die) or <0.2 (predicted to live) whose outcomes were opposite to that predicted had twice the ICU LOS compared with patients whose outcomes were consistent with prediction.
In a Canadian medical-surgical ICU, patients with ICU LOS > or = 14 days accounted for 7.3% of total admissions but consumed 43.5% of total ICU days. Identification of patients with prolonged ICU LOS who would ultimately die in the ICU may lead to earlier withdrawal of therapy in these patients, resulting in a substantial reduction in suffering and cost savings. In our study population, outcome prediction using the APACHE II equation did not provide sufficient power to accurately discriminate between nonsurvivors and survivors.
分析加拿大一所内科-外科重症监护病房(ICU)的ICU住院日使用情况,并确定ICU住院时间延长(LOS)的患者。
前瞻性描述性研究。
加拿大一家三级医疗内科-外科ICU。
连续入住成人内科-外科ICU的患者。神经外科、心脏外科和冠心病监护病房患者被排除。
对于每次ICU入院,收集患者的人口统计学资料、诊断、急性生理与慢性健康状况评估II(APACHE II)评分、ICU住院时间和医院死亡率。使用APACHE II方程计算患者的死亡风险。入院患者按ICU住院时间分为四组:1至2天、3至6天、7至13天和≥14天。在这四个住院时间组中,比较ICU住院日数量以及观察到的和预测的死亡率。入院患者还按死亡风险分为五个概率范围五分位数。在这五个风险组中,比较存活者和非存活者的ICU住院时间。
共有1960例入院患者,使用了9298个ICU住院日。ICU住院时间(均值±标准误)为4.74±0.2(中位数为2;范围为1至178)天。短期住院患者(ICU住院时间≤2天)占总入院人数的60.3%,但仅消耗了总ICU住院日的16.4%。长期住院患者(ICU住院时间≥14天)占总入院人数的7.3%,但消耗了总ICU住院日的43.5%。在长期住院患者中,最常见的入院原因是肺炎、多发伤、神经肌肉无力和感染性休克。长期住院患者的死亡率接近50%。按患者死亡风险分析时,死亡风险>0.8(预测死亡)或<0.2(预测存活)且结局与预测相反的患者,其ICU住院时间是结局与预测一致的患者的两倍。
在加拿大一所内科-外科ICU中,ICU住院时间≥14天的患者占总入院人数的7.3%,但消耗了总ICU住院日的43.5%。识别最终会在ICU死亡的ICU住院时间延长患者,可能会使这些患者更早地停止治疗,从而大幅减轻痛苦并节省费用。在我们的研究人群中,使用APACHE II方程进行结局预测并不能提供足够的能力来准确区分非存活者和存活者。