接触硫化氢对嗅觉系统的长期影响。
Long-term effects on the olfactory system of exposure to hydrogen sulphide.
作者信息
Hirsch A R, Zavala G
机构信息
Smell and Taste Treatment and Research Foundation, Chicago, IL 60611, USA.
出版信息
Occup Environ Med. 1999 Apr;56(4):284-7. doi: 10.1136/oem.56.4.284.
OBJECTIVE
To study chronic effects of hydrogen sulphide (H2S) on cranial nerve I (nervi olfactorii), which have been only minimally described.
METHODS
Chemosensations (smell and taste) were evaluated in eight men who complained of continuing dysfunction 2-3 years after the start of occupational exposure to H2S. Various bilateral (both nostrils) and unilateral (one nostril at a time) odour threshold tests with standard odorants as well as the Chicago smell test, a three odour detection and identification test and the University of Pennsylvania smell identification test, a series of 40 scratch and sniff odour identification tests were administered.
RESULTS
Six of the eight patients showed deficits of various degrees. Two had normal scores on objective tests, but thought that they continued to have problems. H2S apparently can cause continuing, sometimes unrecognised olfactory deficits.
CONCLUSION
Further exploration into the extent of such problems among workers exposed to H2S is warranted.
目的
研究硫化氢（H₂S）对嗅神经（第一对脑神经）的慢性影响，目前对此方面的描述极少。
方法
对8名男性进行化学感觉（嗅觉和味觉）评估，这些男性在开始职业性接触H₂S 2至3年后仍抱怨存在持续功能障碍。使用标准气味剂进行各种双侧（双侧鼻孔）和单侧（每次一个鼻孔）气味阈值测试，以及芝加哥嗅觉测试（一种三种气味检测和识别测试）和宾夕法尼亚大学嗅觉识别测试（一系列40种刮擦嗅闻气味识别测试）。
结果
8名患者中有6名表现出不同程度的缺陷。2名患者在客观测试中得分正常，但认为自己仍有问题。H₂S显然可导致持续的、有时未被认识到的嗅觉缺陷。
结论
有必要进一步探究接触H₂S的工人中此类问题的严重程度。
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