Soyannwo M A, Gadallah M, Hams J, Kurashi N Y, el-Essawi O, Khan N A, Singh R G, Alamri A, Beyari T H
Nephrology Unit, King Fahd Specialist Hospital (KFSH), Buraidah, Gassim, Saudi Arabia.
Afr J Med Med Sci. 1998 Mar-Jun;27(1-2):17-21.
As part of our studies in prevent nephrology, we have recorded causal blood pressure during a total population cross-sectional survey of the Faizia East Primary Health District of Buraidah (FEPHD), capital of Gassim region of Saudi Arabia. Out of 5671 subjects whose blood pressure could be recorded, 2222 were above 19 years of age and constituted our adult population. For this report, hypertension have been defined as equal to and greater than 140/90 mm Hg. Total hypertensive population had been divided into three subsets, based on this basic definition, namely combined systolic and diastlic hypertension (S/DHPN), isolated systolic hypertension (ISHPN) and isolated diastolic hypertension (IDHPN), a format which is not generally clear in previous studies on the subject. The overall prevalence of systemic hypertension was found to be 23.58%, which is lower than the figure of 36% for USA (pre-primary prevention intensive campaign). It is assumed that all the three subsets mentioned above have been used in calculating the latter. Although males tended to be more hypertensive than females (OR = 1.22; Chi Square = 3.89; P = 0.05; C.I.: 1.00 < OR < 1.49), the marginal difference (25.7% vs 22.10%) was largely due to the IDHPN subset (OR = 1.73; Chi Square = 4.48; P = 0.034; C.I.: 1.01 < OR < 2.96). In both the S/DHPN and ISHPN: statistical significance was not achieved. Significantly, ISHPN subset constituted the bulk--56.68%--of the hypertensive population while IDHPN constituted the least--11.64%. When analysed into 10-year-age cohorts, ISHPN showed the steepest rise in prevalence with age. Rather suprisingly, the IDHPN did not rise with advancing age while the S/DHPN slope was in between the two. We are unable to identify this pattern in our literature search on the subject. We cannot assess its significance by this study, but we wonder whether or not it carries any prognostic significance in terms of target organ damage. It is possible that this pattern may be peculiar to the sub-region but it certainly is not spurious and in our view deserves further scrutiny. We wish to suggest that clear definition of the three subsets of hypertensive population should be mandatory when defining prevalence. This may provide some further clues in the prognosis and pathogenesis of target organ damage.
作为我们预防肾脏病学研究的一部分,我们在沙特阿拉伯盖西姆地区首府布赖代的法伊齐亚东部初级卫生保健区(FEPHD)的全人群横断面调查中记录了因果血压。在5671名能够记录血压的受试者中,2222人年龄在19岁以上,构成了我们的成年人群。在本报告中,高血压被定义为等于或高于140/90毫米汞柱。根据这一基本定义,高血压总人群被分为三个亚组,即收缩压和舒张压合并高血压(S/DHPN)、单纯收缩期高血压(ISHPN)和单纯舒张期高血压(IDHPN),这种分类方式在以往关于该主题的研究中并不常见。发现系统性高血压的总体患病率为23.58%,低于美国的36%(初级预防强化运动前)。据推测,上述三个亚组均用于计算后者。尽管男性高血压患者往往多于女性(OR = 1.22;卡方 = 3.89;P = 0.05;置信区间:1.00 < OR < 1.49),但这种微小差异(25.7%对22.10%)主要归因于IDHPN亚组(OR = 1.73;卡方 = 4.48;P = 0.034;置信区间:1.01 < OR < 2.96)。在S/DHPN和ISHPN中:均未达到统计学显著性。值得注意的是,ISHPN亚组占高血压人群的大部分——56.68%——而IDHPN占比最小——11.64%。当按10岁年龄组进行分析时,ISHPN的患病率随年龄增长上升最为陡峭。相当令人惊讶的是,IDHPN患病率并未随年龄增长而上升,而S/DHPN的斜率介于两者之间。在我们对该主题的文献检索中未能识别出这种模式。我们无法通过本研究评估其意义,但我们想知道它在靶器官损害方面是否具有任何预后意义。这种模式可能是该次区域所特有的,但肯定不是虚假的,我们认为值得进一步研究。我们建议在定义患病率时,对高血压人群的三个亚组进行明确界定应成为强制性要求。这可能会为靶器官损害的预后和发病机制提供一些进一步的线索。