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1993年韩国私立胸部诊所中细菌性肺结核的治疗情况

Treatment of bacillary pulmonary tuberculosis at the chest clinics in the private sector in Korea, 1993.

作者信息

Hong Y P, Kim S J, Lee E G, Lew W J, Bai J Y

机构信息

Korean Institute of Tuberculosis/Korean National Tuberculosis Association, Seoul.

出版信息

Int J Tuberc Lung Dis. 1999 Aug;3(8):695-702.

Abstract

SETTING

Cohort study of bacillary pulmonary tuberculosis patients treated at private sector chest clinics in Korea.

OBJECTIVE

To assess the treatment behaviour of physicians in private chest clinics and the treatment outcomes of their patients.

DESIGN

  1. A retrospective analysis of a cohort of patients admitted from July through October in 1993, and 2) comparison with results from health centres under the National Tuberculosis Programme (NTP).

RESULTS

Nine hundred and sixty bacillary patients (507 newly diagnosed--'new', and 453 retreatment--'old') were admitted to the study. Initial smears and cultures were not performed in 7% and 21%, and follow-up smears and cultures not done in 19% and 28%, respectively. The regimens prescribed were variable: 23 in 'new' and 72 in 'old' patients, 86 in total. Six-month short-course treatment using HRZE was prescribed for 26.2% of 'new' patients. In many instances, the planned treatment duration was excessive. The success rates (cured plus completed) for 'new' and 'old' patients were 74% and 51%, respectively. The failure rates were less than 1% in 'new' and 9% in 'old' patients.

CONCLUSION

Prescribed regimens were variable in terms of drug combinations and treatment duration. Overall treatment outcome was inferior to that of the health centres under the NTP.

摘要

背景

对在韩国私立胸部诊所接受治疗的细菌性肺结核患者进行队列研究。

目的

评估私立胸部诊所医生的治疗行为及其患者的治疗结果。

设计

1)对1993年7月至10月收治的一组患者进行回顾性分析,2)与国家结核病规划(NTP)下的健康中心的结果进行比较。

结果

960例细菌性患者(507例新诊断——“新”,453例复治——“旧”)纳入研究。分别有7%和21%的患者未进行初始涂片和培养,19%和28%的患者未进行随访涂片和培养。所开的治疗方案各不相同:“新”患者有23种,“旧”患者有72种,共86种。26.2%的“新”患者采用HRZE进行6个月短程治疗。在许多情况下,计划的治疗疗程过长。“新”患者和“旧”患者的成功率(治愈加完成治疗)分别为74%和51%。“新”患者的失败率低于1%,“旧”患者的失败率为9%。

结论

所开治疗方案在药物组合和治疗疗程方面各不相同。总体治疗结果不如国家结核病规划下健康中心的治疗结果。

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