帕克斯6：掌控眼睛形态发生与眼睛进化

Pax 6: mastering eye morphogenesis and eye evolution.

作者信息

Gehring W J, Ikeo K

机构信息

Department of Cell Biology, Biozentrum, University of Basel, Klingelbergstrasse 70, 4056 Basel, Switzerland.

出版信息

Trends Genet. 1999 Sep;15(9):371-7. doi: 10.1016/s0168-9525(99)01776-x.

DOI:10.1016/s0168-9525(99)01776-x

PMID:10461206

Abstract

Pax 6 genes from various animal phyla are capable of inducing ectopic eye development, indicating that Pax 6 is a master control gene for eye morphogenesis. It is proposed that the various eye-types found in metazoa are derived from a common prototype, monophyletically, by a mechanism called intercalary evolution.

摘要

来自不同动物门的Pax 6基因能够诱导异位眼发育，这表明Pax 6是眼睛形态发生的主控基因。有人提出，后生动物中发现的各种眼型是通过一种称为居间进化的机制单系地从一个共同的原型衍生而来的。