果蝇胚胎中枢神经系统中的神经胶质细胞发育。

Glia development in the embryonic CNS of Drosophila.

作者信息

Granderath S, Klämbt C

机构信息

Institut für Neurobiologie Universität Münster Badestrasse 9, D-48149, Münster, Germany.

出版信息

Curr Opin Neurobiol. 1999 Oct;9(5):531-6. doi: 10.1016/S0959-4388(99)00008-2.

DOI:10.1016/S0959-4388(99)00008-2

PMID:10508736

Abstract

Glial cells are pivotal players during the development and function of complex nervous systems. In Drosophila, recent genetic analyses have revealed several genes that control differentiation and function of CNS glial cells and their interactions with neurons can be studied in detail at the CNS midline, where it is essential for the correct establishment of the commissural axon pattern.

摘要

神经胶质细胞在复杂神经系统的发育和功能中起着关键作用。在果蝇中，最近的遗传学分析揭示了几个控制中枢神经系统神经胶质细胞分化和功能的基因，并且可以在中枢神经系统中线详细研究它们与神经元的相互作用，而中枢神经系统中线对于正确建立连合轴突模式至关重要。