van Loon C J, Wijers M M, de Waal Malefijt M C, Buma P, Veth R P
Department of Orthopedics, University of Nijmegen, The Netherlands.
Acta Orthop Belg. 1999 Sep;65(3):357-63.
The purpose of this study was to evaluate the clinical and radiographic results of TKA's with morsellized and solid femoral bone grafting. From April 1989 to February 1996, 6 primary and 18 revision TKA's with femoral bone grafting were performed in 22 patients with an average age of 62 years. Eleven knees were affected by rheumatoid arthritis, 10 by osteoarthritis, 2 by osteonecrosis and one by hemophiliac arthropathy. The femoral bone defects were large in 12, medium in 9, small in 3, contained in 10 and uncontained in 14 cases. Reconstruction was done with impacted morsellized fresh frozen trabecular bone grafts in 13 knees, with solid bone grafts in 7 knees and with combined grafts in 4 knees. Twenty-one cases were clinically evaluated at an average of 38 months (range: 9-89 months). The average Knee Society knee score increased by 39 points to 85 points at follow-up. The average functional score increased by 22 points to 48 points. Two cases with solid femoral bone grafts failed due to aseptic loosening. There were no infections. Radiographic follow-up revealed osteopenia around the femoral component in 10 knees. Two knees showed circumferential radiolucency around the femoral stem, and 5 knees had minor radiolucency at the anterior part of the femoral component. Radiographic incorporation was present in 5 of the 6 cases that could be evaluated. Histologic analysis of two biopsies revealed incorporation of the morsellized bone graft. The authors advocate impacted morsellized bone grafting for contained and small-to-medium uncontained femoral bone defects in combination with cemented TKA.
本研究的目的是评估采用股骨碎骨植骨和实体股骨植骨的全膝关节置换术(TKA)的临床和影像学结果。1989年4月至1996年2月,对22例平均年龄62岁的患者实施了6例初次和18例翻修的股骨植骨全膝关节置换术。11例膝关节受类风湿关节炎影响,10例受骨关节炎影响,2例受骨坏死影响,1例受血友病性关节病影响。股骨骨缺损12例为大型,9例为中型,3例为小型,10例为包容型,14例为非包容型。13例膝关节采用打压植骨的新鲜冷冻小梁骨碎骨进行重建,7例采用实体骨移植,4例采用联合移植。21例患者接受了平均38个月(范围:9 - 89个月)的临床评估。随访时,膝关节协会膝关节平均评分提高了39分,达到85分。平均功能评分提高了22分,达到48分。2例采用实体股骨植骨的患者因无菌性松动失败。无感染发生。影像学随访显示10例膝关节股骨假体周围有骨质减少。2例膝关节股骨柄周围出现环形透亮区,5例膝关节股骨假体前部有轻微透亮区。在6例可评估的病例中,5例有影像学骨融合。对两份活检组织的组织学分析显示碎骨植骨已融合。作者主张对于包容型以及中小型非包容型股骨骨缺损,采用打压植骨碎骨并结合骨水泥固定的全膝关节置换术。