May J, White G H, Waugh R, Chaufour X, Stephen M S, Yu W, Harris J P
Department of Surgery, University of Sydney, Sydney, Australia.
Eur J Vasc Endovasc Surg. 1999 Oct;18(4):344-8. doi: 10.1053/ejvs.1999.0899.
to compare the outcome of patients whose abdominal aortic aneurysm (AAA) ruptured following endoluminal repair with those whose AAA ruptured prior to treatment.
over a 4-year period 434 patients underwent treatment for AAA with conventional open (n=253) and endoluminal repair (n=181). Of those having open repair, 216 patients had elective operations while 41 had operations for ruptured AAA. Four patients with ruptured AAA had undergone endoluminal repair previously (Group I) while the remaining 37 patients ruptured de novo (Group II). The patients in both groups were similar in age and sex but differed clinically. All four patients in Group I had major medical co-morbidities versus 56% in Group II (p<0.05). All patients in group I had a known endoleak following endoluminal repair. All patients underwent open repair.
the proportion of patients presenting with hypotension in Group I (1/4) was significantly less than in Group II (30/37). The difference in 30-day mortality for Group I (0%) compared with that for Group II (43%) was significant. The four patients in Group I remain alive and well at follow-up 22 months after operation. The outcome for Group I was better than Group II despite the higher incidence of medical co-morbidities.
endoluminal AAA repair complicated by a persistent endoleak does not protect from rupture, which may not be accompanied by such major haemodynamic changes and high mortality as rupture de novo. Further long-term results in more patients are required to confirm this intermediate level of protection.
比较腹主动脉瘤(AAA)腔内修复术后破裂患者与治疗前破裂患者的治疗结果。
在4年时间里,434例患者接受了AAA治疗,其中传统开放手术(n = 253)和腔内修复术(n = 181)。在接受开放修复的患者中,216例患者接受了择期手术,41例患者接受了AAA破裂修复手术。4例AAA破裂患者此前接受过腔内修复术(I组),其余37例患者为新发破裂(II组)。两组患者在年龄和性别上相似,但临床情况不同。I组的所有4例患者都有严重的内科合并症,而II组为56%(p<0.05)。I组的所有患者在腔内修复术后都有已知的内漏。所有患者均接受了开放修复。
I组出现低血压的患者比例(1/4)明显低于II组(30/37)。I组30天死亡率(0%)与II组(43%)相比差异显著。I组的4例患者在术后22个月的随访中仍存活且状况良好。尽管内科合并症发生率较高,但I组的治疗结果优于II组。
腔内AAA修复术并发持续性内漏并不能防止破裂,这种破裂可能不会伴有像新发破裂那样的严重血流动力学变化和高死亡率。需要更多患者的进一步长期结果来证实这种中等程度的保护作用。