Wessling-Resnick M
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA.
Crit Rev Biochem Mol Biol. 1999;34(5):285-314. doi: 10.1080/10409239991209318.
Recent information gained from genetic and biochemical studies of iron transport in yeast, coupled with the identification of specific mutations causing iron uptake disorders in mice and man, has provided new clues about the mechanisms involved in iron uptake. This article summarizes these discoveries and discusses their impact on our current understanding of the biochemistry of iron uptake.
最近从酵母中铁转运的遗传和生化研究中获得的信息,再加上对导致小鼠和人类铁摄取障碍的特定突变的鉴定,为铁摄取所涉及的机制提供了新线索。本文总结了这些发现,并讨论了它们对我们目前对铁摄取生物化学理解的影响。