Cherland E, Fitzpatrick R
Department of Psychiatry, Royal University Hospital, Saskatoon, Saskatchewan.
Can J Psychiatry. 1999 Oct;44(8):811-3. doi: 10.1177/070674379904400810.
To examine the rate of psychotic and mood-congruent psychotic side effects of stimulant medications in children treated for attention-deficit hyperactivity disorder (ADHD).
A chart review was completed of all children diagnosed with ADHD in an outpatient clinic from January 1989 to March 1995.
Over 5 years, 192 children were diagnosed with ADHD. Ninety-eight children received treatment at the clinic with stimulants. Six children developed psychotic or mood-congruent psychotic symptoms during treatment. Children on medication were followed for an average of 1 year and 9 months.
Awareness of the potential for psychotic side effects from stimulant medications is important when prescribing for children. A large prospective study would be useful to predict the frequency and classification of the side effects in children.
研究在接受注意力缺陷多动障碍(ADHD)治疗的儿童中,使用兴奋剂药物出现精神病性及心境一致的精神病性副作用的发生率。
对1989年1月至1995年3月在门诊被诊断为ADHD的所有儿童进行病历回顾。
在5年多的时间里,192名儿童被诊断为ADHD。98名儿童在诊所接受了兴奋剂治疗。6名儿童在治疗期间出现了精神病性或心境一致的精神病性症状。接受药物治疗的儿童平均随访了1年9个月。
在给儿童开处方时,意识到兴奋剂药物可能产生精神病性副作用很重要。一项大型前瞻性研究将有助于预测儿童副作用的发生率和分类。