Borghi A, Agnoletti G, Valsecchi O, Carminati M
Department of Cardiology, Ospedali Riuniti, via Mazzini 12, Bergamo, Italy.
Heart. 1999 Dec;82(6):e10. doi: 10.1136/hrt.82.6.e10.
To review 12 years of experience of balloon aortic valvoplasty in childhood.
Early and mid-term clinical and instrumental evaluation of 104 consecutive balloon aortic valvoplasties performed from 1986 to 1998.
A tertiary referral centre for congenital heart disease.
90 patients with congenital aortic stenosis: 20 neonates (group 1), 16 infants (group 2), and 54 children (group 3).
Balloon aortic valvotomy.
Doppler and peak to peak aortic gradient before and after valvoplasty, degree of aortic regurgitation before and after valvoplasty, early and late mortality, need for repeat intervention or surgery.
Balloon aortic valvoplasty produced a gradient reduction of > 50% in 59 patients, 12 having a residual peak to peak gradient of > 50 mm Hg. Early mortality included three procedure related and six procedure unrelated deaths. There were no intraprocedural deaths. Grade III aortic regurgitation occurred in 20 patients. Five non-lethal complications occurred. At a mean follow up of 5.1 (group 1), 5.7 (group 2), and 7.6 years (group 3), survival was 75%, 88%, and 96%, respectively. Redilatation was performed in three patients in group 1, one in group 2, and 10 in group 3. Surgery was necessary for six in group 1, one in group 2, and eight in group 3. Freedom from events at last follow up was 50%, 75%, and 64%, respectively. There was a residual maximum Doppler gradient of < 30 mm Hg in 22 patients and > 60 mm Hg in 23; 50 patients have mild to moderate aortic regurgitation.
Balloon aortic valvoplasty is effective and repeatable and offers good palliation for congenital aortic stenosis in childhood.
回顾儿童期球囊主动脉瓣成形术12年的经验。
对1986年至1998年连续进行的104例球囊主动脉瓣成形术进行早期和中期临床及器械评估。
一家先天性心脏病三级转诊中心。
90例先天性主动脉瓣狭窄患者:20例新生儿(1组),16例婴儿(2组),54例儿童(3组)。
球囊主动脉瓣切开术。
瓣膜成形术前和术后的多普勒及峰-峰主动脉压差、瓣膜成形术前和术后的主动脉反流程度、早期和晚期死亡率、再次干预或手术的必要性。
球囊主动脉瓣成形术使59例患者的压差降低>50%,其中12例残余峰-峰压差>50 mmHg。早期死亡包括3例与手术相关和6例与手术无关的死亡。术中无死亡病例。20例患者发生Ⅲ级主动脉反流。发生5例非致命性并发症。1组平均随访5.1年,2组平均随访5.7年,3组平均随访7.6年,生存率分别为75%、88%和96%。1组3例、2组1例、3组10例患者进行了再次扩张。1组6例、2组1例、3组8例患者需要进行手术。末次随访时无事件发生的比例分别为50%、75%和64%。22例患者残余最大多普勒压差<30 mmHg,23例患者>60 mmHg;50例患者有轻至中度主动脉反流。
球囊主动脉瓣成形术有效且可重复,为儿童先天性主动脉瓣狭窄提供了良好的姑息治疗。