Utsugi K, Hirai Y, Takeshima N, Akiyama F, Sakurai S, Hasumi K
Cancer Institute Hospital, Department of Pathology, Cancer Institute, 1-37-1, Kami-Ikebukuro, Toshima-ku, Tokyo, 170-8455, Japan.
Gynecol Oncol. 1999 Dec;75(3):345-8. doi: 10.1006/gyno.1999.5622.
The aim of this study was to qualify a staining technique for the diagnosis of adenoma malignum.
The gastric mucin expression of adenoma malignum, ordinary endocervical adenocarcinoma, and normal cervical glands was immunohistochemically compared using the monoclonal antibody HIK1083.
The three categories were clearly distinguished, with 90% (9/10) of cases with positive adenoma malignum, 30% (3/10) of cases with weakly positive ordinary cervical adenocarcinoma, and no (0/10) cases of positive normal cervical glands.
This preliminary report indicates that the use of HIK1083 is valuable in the diagnosis of adenoma malignum.
本研究的目的是鉴定一种用于诊断恶性腺瘤的染色技术。
使用单克隆抗体HIK1083对恶性腺瘤、普通宫颈腺癌和正常宫颈腺的胃粘蛋白表达进行免疫组化比较。
这三类情况可明显区分,恶性腺瘤病例中有90%(9/10)呈阳性,普通宫颈腺癌病例中有30%(3/10)呈弱阳性,正常宫颈腺病例中无一例(0/10)呈阳性。
本初步报告表明,使用HIK1083在恶性腺瘤的诊断中具有重要价值。