Friedman M, Tanyeri H, Lim J W, Landsberg R, Vaidyanathan K, Caldarelli D
Department of Otolaryngology, Rush-Presbyterian-Saint Luke's Medical Center, Chicago, Illinois, USA.
Otolaryngol Head Neck Surg. 2000 Jan;122(1):71-4. doi: 10.1016/S0194-5998(00)70147-1.
The goal was to compare the effect of an improved nasal airway on obstructive sleep apnea (OSA) by use of subjective and objective measures.
A prospective study of 50 consecutive patients with nasal airway obstruction and OSA was carried out.
Subjectively, nasal breathing improved in 49 (98%) patients, whereas snoring decreased or disappeared in 17 (34%); the remaining 33 (66%) patients did not notice any significant change in their snoring. Daytime energy levels increased in 39 (78%) patients and remained unchanged or worsened in 11 (22%). In review of the polysomnographic data, the group overall did not have significant changes in respiratory disturbance index (RDI) or lowest oxygen saturation levels (LSaO(2)). Continuous positive airway pressure (CPAP) levels required to correct OSA decreased after nasal surgery (P < 0.01). Patients with mild OSA showed significant worsening in RDI (P < 0.05), whereas LSaO(2) levels were improved in the group with moderate OSA (P < 0.05). In patients with severe OSA neither the RDI levels nor the LSaO(2) changed, but CPAP levels required to alleviate the obstruction after surgery were reduced (P < 0.01).
Most patients report improvement in nasal and sleep symptoms after correction of nasal airway obstruction. However, nasal surgery alone does not consistently improve OSA when measured objectively. Depending on the severity of OSA, nasal airway reconstruction may contribute to a decrease in CPAP level and improvement in oxygen saturation. Correction of the obstructed nasal airway should certainly be included in the overall treatment plan for OSA.
通过主观和客观测量方法比较改善鼻气道对阻塞性睡眠呼吸暂停(OSA)的影响。
对50例连续性鼻气道阻塞合并OSA患者进行前瞻性研究。
主观上,49例(98%)患者鼻呼吸改善,17例(34%)患者打鼾减轻或消失;其余33例(66%)患者未注意到打鼾有任何显著变化。39例(78%)患者白天精力水平提高,11例(22%)患者保持不变或恶化。回顾多导睡眠图数据,该组总体呼吸紊乱指数(RDI)或最低血氧饱和度水平(LSaO₂)无显著变化。鼻手术后纠正OSA所需的持续气道正压通气(CPAP)水平降低(P < 0.01)。轻度OSA患者RDI显著恶化(P < 0.05),而中度OSA组LSaO₂水平改善(P < 0.05)。重度OSA患者RDI水平和LSaO₂均无变化,但手术后缓解阻塞所需的CPAP水平降低(P < 0.01)。
大多数患者在鼻气道阻塞纠正后报告鼻和睡眠症状改善。然而,单纯鼻手术在客观测量时并不能持续改善OSA。根据OSA的严重程度,鼻气道重建可能有助于降低CPAP水平和改善血氧饱和度。纠正阻塞性鼻气道肯定应纳入OSA的整体治疗计划。