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用于体外研究的低杂散极低频磁场暴露系统。

Low stray ELF magnetic field exposure system for in vitro study.

作者信息

Yamazaki K, Fujinami H, Shigemitsu T, Nishimura I

机构信息

Central Research Institute of Electric Power Industry, Tokyo, Japan.

出版信息

Bioelectromagnetics. 2000 Feb;21(2):75-83. doi: 10.1002/(sici)1521-186x(200002)21:2<75::aid-bem1>3.0.co;2-c.

Abstract

An exposure facility for wide application to cell exposure to an ELF (extremely low frequency) magnetic field was developed. It is suitable for conducting experiments under a high-intensity, variable-frequency magnetic field, on the biological effects of the ELF magnetic field in an in vitro study. The exposure system consists of Merritt's 4-square coil as a basic component to generate the required magnetic field intensity of 10 mT at 50 Hz with spatial field uniformity less than +/-3% in a 400 mm cube. Concentric compensation coils are adopted to eliminate the effects of stray fields on sham (control) samples in the vicinity of the exposure system. The uniformity of the magnetic field in the exposure coil, the increase in the power supply capacity due to the existence of compensation coils, and the stray field estimation were investigated carefully. After fabricating the system, performance tests were carried out and all the characteristics were found to be satisfactory. In addition, the ideal configuration for a concentric coil system was proposed.

摘要

开发了一种广泛应用于细胞暴露于极低频(ELF)磁场的暴露装置。它适用于在高强度、可变频率磁场下进行体外研究中ELF磁场生物效应的实验。该暴露系统以梅里特四方线圈为基本组件,在50Hz时产生所需的10mT磁场强度,在400mm立方体中的空间场均匀度小于+/-3%。采用同心补偿线圈来消除暴露系统附近杂散场对假(对照)样品的影响。仔细研究了暴露线圈中磁场的均匀性、由于补偿线圈的存在而导致的电源容量增加以及杂散场估计。制造系统后进行了性能测试,发现所有特性均令人满意。此外,还提出了同心线圈系统的理想配置。

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