Janssens R M, Lambalk C B, Vermeiden J P, Schats R, Schoemaker J
Institute for Endocrinology, Reproduction and Metabolism, IVF Center, Vrije Universiteit Medical Center, Amsterdam, The Netherlands.
Hum Reprod. 2000 Feb;15(2):314-8. doi: 10.1093/humrep/15.2.314.
The results of in-vitro fertilization in natural cycles (NIVF) in women with tubal infertility at our department are presented. The study had a prospective design. We needed 75 cycles in 50 patients to obtain one oocyte from each patient. Successful oocyte recovery rate was 67% per started cycle and 82% per oocyte retrieval. Thirty-five embryos were transferred and resulted in four ongoing pregnancies (5.3% per cycle, 6.5% per oocyte retrieval, 11.4% per embryo transfer and 11.4% per embryo). Six patients who participated in the study made a second attempt at NIVF. Five of them conceived of which four were ongoing. Cumulative ongoing pregnancy rates are 9. 8% per cycle, 11.9% per oocyte retrieval, 19.5% per embryo transfer and 19.5% per embryo. We conclude that NIVF is an easy, cheap and realistic method to obtain a pregnancy for patients with tubal infertility.
本文展示了我院对输卵管性不孕女性进行自然周期体外受精(NIVF)的结果。该研究采用前瞻性设计。我们需要50名患者进行75个周期,以便从每位患者获取一个卵母细胞。每个启动周期的卵母细胞成功回收率为67%,每次取卵的成功率为82%。共移植了35个胚胎,结果有4例持续妊娠(每个周期5.3%,每次取卵6.5%,每次胚胎移植11.4%,每个胚胎11.4%)。6名参与研究的患者进行了第二次NIVF尝试。其中5名受孕,4例持续妊娠。累积持续妊娠率为每个周期9.8%,每次取卵11.9%,每次胚胎移植19.5%,每个胚胎19.5%。我们得出结论,对于输卵管性不孕患者,NIVF是一种简便、廉价且切实可行的妊娠获取方法。