[A case of epilepsy with agammaglobulinemia improved by intravenous immunoglobulin therapy].

We report a 13-year-old boy having epilepsy with agammaglobulinemia. He developed without neurological deficits until the age of 4 years, when he had convulsive generalized status epilepticus. He suffered from recurrent infections, and the diagnosis of agammaglobulinemia was made at 5 years. At 8 years, he had complex partial seizures following an aura of epigastric discomfort. EEG recording showed right anteriotemporal spikes. He was diagnosed as having epilepsy and treated by antiepileptic drugs without success. At 10 years, intravenous immunoglobulin therapy was begun to treat recurrent infections. This therapy not only prevented infections, but also resulted in marked improvement of his epilepsy, both clinically and electroencephalographically.