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Oligomerization of deoxyguanosine 5'-phosphoro-2-methylimidazolide on a polycytidylate template.

作者信息

Kozlov I A, Orgel L E

机构信息

Salk Institute for Biological Studies, San Diego, CA 92186, USA.

出版信息

Orig Life Evol Biosph. 1999 Dec;29(6):593-5. doi: 10.1023/a:1006666926870.

Abstract

The oligomerization of deoxyguanosine 5'-phosphoro-2-methylimidazolide on a polycytidylate template is much less efficient than the oligomerization of the corresponding activated ribonucleotide. Nonetheless oligomers containing up to eight nucleotide residues are detected. The products are 3'-5'-linked oligodeoxyribonucleotides capped at the 5'-terminus with a pyrophosphate-linked monomer.

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