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通过联合使用洗必泰和过硼酸盐减少牙菌斑、牙菌斑和牙龈炎

Stain, plaque and gingivitis reduction by combining chlorhexidine and peroxyborate.

作者信息

Gründemann L J, Timmerman M F, Ijzerman Y, van der Weijden G A, van der Weijden G A

机构信息

Department of Periodontology, ACTA, The Netherlands.

出版信息

J Clin Periodontol. 2000 Jan;27(1):9-15. doi: 10.1034/j.1600-051x.2000.027001009.x.

Abstract

BACKGROUND

Previous studies have shown that using an oxidising agent in addition to chlorhexidine reduces staining.

AIM

The purpose of the present study was to investigate whether, compared to chlorhexidine alone, the use of an oxidising mouthrinse as an adjunct to chlorhexidine is efficacious in reducing stain, plaque and gingivitis.

METHOD

This study had a single-blind, 2-group parallel design, including a 14-day experimental non-brushing period during which 1 group (n= 14) used chlorhexidine alone (CHX) (chlorhexidine mouthrinse, 0.12% Oral-B laboratories, Ireland), and the other (n= 14) used chlorhexidine in combination with an oxidising agent (sodiumperborate-monohydrate-Bocasan, Oral-B laboratories, Ireland). Patients were randomly assigned to either group. All participants received a scaling and polishing before the start of the trial. No oral hygiene instructions were given. Since, at the start of the experiment, all stain and plaque were removed, only the gingival condition was evaluated at baseline by means of bleeding on marginal probing. The examination after 14 days of rinsing included the evaluation of plaque, bleeding on marginal probing and stain (GMSI: gingival modification of the stain index).

RESULTS

The results showed at day 14, a significant difference between the 2 groups for plaque (CHX: 0.18, CHX+PER: 0.08, p=0.03) and gingival bleeding (CHX: 0.38, CHX+PER: 0.21, p<0.001). The proportion of stained surfaces was less in the CHX+PER group (28%), than in the chlorhexidine group (48%) (p=0.04).

CONCLUSIONS

In conclusion, the adjunctive use of an oxidising agent peroxyborate to chlorhexidine, proved to be superior to chlorhexidine alone with regard to the inhibition of plaque and development of gingivitis. In addition, the proportion of stained surfaces was significantly less when adding the oxidising mouthrinse to chlorhexidine.

摘要

背景

先前的研究表明,除洗必泰外使用氧化剂可减少染色。

目的

本研究的目的是调查与单独使用洗必泰相比,使用氧化漱口水作为洗必泰的辅助手段在减少色斑、牙菌斑和牙龈炎方面是否有效。

方法

本研究采用单盲、两组平行设计,包括为期14天的实验性不刷牙期,在此期间,一组(n = 14)单独使用洗必泰(CHX)(0.12%爱尔兰欧乐-B实验室的洗必泰漱口水),另一组(n = 14)使用洗必泰与氧化剂(一水过硼酸钠 - 博卡散,爱尔兰欧乐-B实验室)联合使用。患者被随机分配到两组中的任何一组。所有参与者在试验开始前均接受了洗牙和抛光。未给予口腔卫生指导。由于在实验开始时所有色斑和牙菌斑都已清除,因此仅在基线时通过龈缘探诊出血来评估牙龈状况。冲洗14天后的检查包括对牙菌斑、龈缘探诊出血和色斑(GMSI:色斑指数的牙龈修正值)的评估。

结果

结果显示,在第14天,两组在牙菌斑(CHX:0.18,CHX + PER:0.08,p = 0.03)和牙龈出血(CHX:0.38,CHX + PER:0.21,p < 0.001)方面存在显著差异。CHX + PER组的染色表面比例(28%)低于洗必泰组(48%)(p = 0.04)。

结论

总之,在抑制牙菌斑和牙龈炎发展方面,洗必泰联合使用氧化剂过硼酸盐被证明优于单独使用洗必泰。此外,在洗必泰中添加氧化漱口水时,染色表面的比例显著降低。

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