Matsunaga H, Kiriike N, Miyata A, Iwasaki Y, Matsui T, Fujimoto K, Kasai S, Kaye W H
Department of Neuropsychiatry, Osaka City University Medical School, Osaka, Japan.
Psychiatry Clin Neurosci. 1999 Dec;53(6):661-6. doi: 10.1046/j.1440-1819.1999.00622.x.
This study sought to assess the prevalence and symptomatology of comorbid obsessive-compulsive disorder (OCD) among Japanese subjects who met the DSM-III-R criteria for bulimia nervosa (BN). The Structured Clinical Interview for DSM-III-R Patient Version was used to distinguish 26 BN patients with concurrent OCD from 52 BN patients without OCD. Obsessive-compulsive symptoms in BN subjects with concurrent OCD were evaluated using the Japanese version of the Yale-Brown Obsessive-Compulsive Scale. There were no differences in the prevalence of concurrent OCD between BN subjects with and without a lifetime history of anorexia nervosa. Among BN subjects with concurrent OCD, symptoms related to symmetry and order were most frequently identified, followed by contamination and aggressive obsessions, and checking and cleaning/washing compulsions. Bulimia nervosa subjects with concurrent OCD were more likely than subjects without OCD to have more severe mood and core eating disorder psychopathology. Comorbid OCD is a common phenomenon in Japanese bulimics (33%) similar to that suggested in BN subjects in the Western countries. Obsessive-compulsive symptoms related to symmetry and order were most frequently observed in BN subjects with concurrent OCD, which was a similar finding to that reported among restricting anorexic subjects.
本研究旨在评估符合神经性贪食症(BN)的《精神疾病诊断与统计手册第三版修订版》(DSM-III-R)标准的日本受试者中共病强迫症(OCD)的患病率和症状学。采用《精神疾病诊断与统计手册第三版修订版》患者版结构化临床访谈,从52名无强迫症的神经性贪食症患者中区分出26名并发强迫症的神经性贪食症患者。使用耶鲁-布朗强迫症量表日语版对并发强迫症的神经性贪食症患者的强迫症状进行评估。有神经性厌食症终生病史和无此病史的神经性贪食症患者并发强迫症的患病率没有差异。在并发强迫症的神经性贪食症患者中,与对称和秩序相关的症状最为常见,其次是污染和攻击性强迫观念,以及检查和清洁/洗涤强迫行为。并发强迫症的神经性贪食症患者比无强迫症的患者更有可能出现更严重的情绪和核心饮食障碍精神病理学症状。共病强迫症在日本神经性贪食症患者中是一种常见现象(33%),与西方国家神经性贪食症患者中的情况相似。在并发强迫症的神经性贪食症患者中,与对称和秩序相关的强迫症状最为常见,这一发现与限制型神经性厌食症患者中的报告相似。