Jünger C, Rathmann W, Giani G
Abteilung Biometrie und Epidemiologie, Deutsches Diabetes-Forschungsinstitut an der Heinrich-Heine-Universität Düsseldorf.
Dtsch Med Wochenschr. 2000 Feb 4;125(5):103-9. doi: 10.1055/s-2007-1023954.
In spite of the great importance of diabetes in Germany, little is known about the medical treatment of diabetic patients by primary health care practices and the effects of the drug budget, introduced by the German Health Care Structure Reform Act (GSG) from 1993.
Computerized data (MediPlus, IMS HEALTH) on prescriptions of the most important drugs were analysed in 2892 diabetic patients of 362 primary care physicians for the period of July 1992 to December 1994.
There was an initial decrease in prescriptions per treated patient of antidiabetic drugs and antihypertensive drugs according to the GSG, which was not maintained during the study period. Nevertheless, a cost saving per treated patient with respect to beta-blocker and ACE inhibitors was observed, mainly as a result of a change of preparations and a drop in drug company sales prices. When beginning of a new therapy with oral antidiabetics, the physicians increasingly used acarbose rather than less expensive sulphonylureas. A previous trend of increased use of ACE inhibitors and diuretics for antihypertensive treatment was maintained. In 1993 and 1994, the number of prescriptions and the prescription costs for lipid lowering drugs decreased compared to the values of the last six months of 1992. A global decrease in prescription use of drugs without proven efficacy observed in the first six months of 1993, did not persist.
The data show, that the drug budget had no relevant long term impact on drug prescribing by internists and general practitioners for diabetic patients.
尽管糖尿病在德国极为重要,但对于初级医疗保健机构对糖尿病患者的药物治疗情况以及1993年德国医疗保健结构改革法案(GSG)引入的药物预算所产生的影响,人们了解甚少。
对362名初级保健医生的2892例糖尿病患者在1992年7月至1994年12月期间最重要药物的处方进行了计算机化数据分析(MediPlus,IMS HEALTH)。
根据GSG,每位接受治疗的患者的抗糖尿病药物和抗高血压药物处方量最初有所下降,但在研究期间并未持续。然而,观察到每位接受治疗的患者在β受体阻滞剂和血管紧张素转换酶抑制剂方面节省了成本,这主要是由于制剂的改变和药品公司销售价格的下降。在开始使用口服抗糖尿病药物进行新治疗时,医生越来越多地使用阿卡波糖而非成本较低的磺脲类药物。此前抗高血压治疗中血管紧张素转换酶抑制剂和利尿剂使用增加的趋势得以维持。与1992年最后六个月的值相比,1月93日和1994年,降脂药物的处方数量和处方成本有所下降。1993年上半年观察到的未经验证疗效的药物处方使用总体下降情况并未持续。
数据表明,药物预算对内科医生和全科医生为糖尿病患者开处方没有长期的相关影响。