Raitio M, Tala E
Dept of Chest Diseases, Turku University Central Hospital, Finland.
Eur Respir J. 2000 Feb;15(2):304-7. doi: 10.1034/j.1399-3003.2000.15b14.x.
Some studies have found that health care workers have an increased risk of tuberculosis, whereas other studies have reported the opposite. This study examined data of Finnish health care workers (HCWs) for the incidence of tuberculosis disease. Cases of occupational tuberculosis in Finland were analysed over a period of 30 yrs (1966-1995). Control subjects were all other incident tuberculosis cases at working age. The material thus obtained included 658 people with notified occupational tuberculosis, and 56,146 control cases. The authors studied incidence, and age specific rate, as well as their trends. The incidence of tuberculosis among health care workers decreased from 57.9 to 6.1 per 100,000 and the corresponding figures among control subjects decreased from 156.8 to 9.1 per 100,000. The overall risk in health care workers was lower than in the general population throughout the study period. Analysis of age specific rates revealed no age group at increased risk. The reasons are multifactorial, among them the successful tuberculosis programme, and the lack of impact of such risk factors as immigration, human immunodeficiency virus infection and drug resistance; high coverage of bacille Calmette-Guérin vaccination may also be a factor, although it is difficult to assess.
一些研究发现医护人员患结核病的风险增加,而其他研究则报告了相反的情况。本研究调查了芬兰医护人员结核病发病的数据。分析了芬兰30年(1966 - 1995年)期间职业性结核病的病例。对照对象为所有其他工作年龄的新发结核病病例。由此获得的资料包括658例报告的职业性结核病患者和56146例对照病例。作者研究了发病率、年龄别发病率及其趋势。医护人员中结核病的发病率从每10万人57.9例降至6.1例,对照对象中的相应数字从每10万人156.8例降至9.1例。在整个研究期间,医护人员的总体风险低于普通人群。年龄别发病率分析显示没有哪个年龄组风险增加。原因是多方面的,其中包括成功的结核病防治计划,以及移民、人类免疫缺陷病毒感染和耐药性等风险因素没有影响;卡介苗接种的高覆盖率也可能是一个因素,尽管难以评估。