Quine S M, Aitken P M, Eccles R
Department of Otolaryngology, University Hospital of Wales, Cardiff, UK.
Acta Otolaryngol. 1999;119(8):911-5. doi: 10.1080/00016489950180270.
The efficacy of the controversial treatment of submucosal diathermy to the inferior turbinates (SMDIT) was evaluated objectively. Twenty-seven patients with chronic rhinitis were investigated by hourly posterior rhinomanometry to assess changes in total and minimum (Fmin) and maximum (Fmax) unilateral nasal airflow over 5 h, before and 2-3 months after standardized SMDIT treatment. Nasal airflow was recorded at a sample pressure of 75 Pa and the results are reported as medians with interquartile range. Whilst SMDIT caused a significant 51% increase (p < 0.0001) in total nasal airflow from 246 cm3/s (131) to 371 cm3/s (133) the changes in unilateral airflow provided further evidence which strongly supported the benefits of this operation. Unilateral Fmin significantly increased by 136% (p < 0.0001) from 69 cm3/s (82) to 163 cm3/s (74) and Fmax significantly increased by 23% (p < 0.0001) from 171 cm3/s (74) to 211 cm3/s (59). The effect of surgery was to "splint" to the turbinate in a state of relative vasoconstriction. Our findings therefore provide functional evidence of submucosal fibrosis following SMDIT. The greater percentage change in unilateral Fmin suggests that this parameter is a more sensitive index of the effect of nasal surgery than total nasal airflow measurements. The importance of considering the nose as two separate airways in the evaluation of nasal treatments is emphasized.
对下鼻甲黏膜下透热疗法(SMDIT)这一颇具争议的治疗方法的疗效进行了客观评估。对27例慢性鼻炎患者在标准化SMDIT治疗前以及治疗后2 - 3个月,通过每小时进行一次后鼻测压法来评估5小时内单侧鼻腔总气流以及最小(Fmin)和最大(Fmax)气流的变化。在75 Pa的采样压力下记录鼻腔气流,结果以中位数及四分位间距报告。虽然SMDIT使总鼻腔气流显著增加了51%(p < 0.0001),从246 cm³/s(131)增至371 cm³/s(133),但单侧气流的变化提供了进一步证据,有力地支持了该手术的益处。单侧Fmin从69 cm³/s(82)显著增加了136%(p < 0.0001)至163 cm³/s(74),Fmax从171 cm³/s(74)显著增加了23%(p < 0.0001)至211 cm³/s(59)。手术的效果是将鼻甲“固定”在相对血管收缩的状态。因此,我们的研究结果为SMDIT术后黏膜下纤维化提供了功能学证据。单侧Fmin的变化百分比更大,表明该参数比总鼻腔气流测量更能敏感地反映鼻腔手术的效果。强调了在评估鼻腔治疗时将鼻腔视为两个独立气道的重要性。