Cloft H J, Jensen M E, Kallmes D F, Dion J E
Department of Radiology, Emory University Hospital, Atlanta, GA 30322, USA.
AJNR Am J Neuroradiol. 2000 Mar;21(3):541-5.
Iatrogenic dissections are an uncommon complication of cerebral angiography. We retrospectively reviewed 12 cases of arterial dissections complicating cerebral angiography and cerebrovascular interventions to evaluate the clinical course of these dissections.
Cases from a large tertiary center performing a large number of neurovascular procedures were collected retrospectively. The patients' medical records and imaging studies were reviewed, with particular attention given to the cause of the dissection, the development of ischemic events resulting from the dissection, and the treatment used.
Each of nine dissections affected a vertebral artery, each of two affected an internal carotid artery, and one affected a common carotid artery. The prevalence of iatrogenic dissections was 0.4%. Seven of the dissections were noted at the time of contrast material injection for the filming of cerebral angiograms. The other five dissections occurred during catheter or wire manipulations for interventional neuroradiologic procedures. Five of the patients in our series were treated with IV administered heparin for 24 to 48 hours. The other seven patients had recently suffered acute intracranial hemorrhage or undergone neurosurgery and could not undergo anticoagulant therapy. None of the patients developed symptoms of ischemia, but one was later found to have an asymptomatic infarct in the territory supplied by the dissected artery.
Arterial dissections are an uncommon complication of cerebral angiography and cerebrovascular interventions and usually have a benign clinical course.
医源性动脉夹层是脑血管造影术罕见的并发症。我们回顾性分析了12例脑血管造影术及脑血管介入治疗并发动脉夹层的病例,以评估这些夹层的临床病程。
回顾性收集一家进行大量神经血管手术的大型三级中心的病例。查阅患者的病历和影像学检查资料,特别关注夹层的原因、夹层导致的缺血性事件的发生情况以及所采用的治疗方法。
9例夹层累及椎动脉,2例累及颈内动脉,1例累及颈总动脉。医源性夹层的发生率为0.4%。7例夹层在注射造影剂进行脑血管造影拍摄时被发现。另外5例夹层发生在介入神经放射学手术的导管或导丝操作过程中。我们系列中的5例患者接受了静脉注射肝素治疗24至48小时。另外7例患者近期发生急性颅内出血或接受了神经外科手术,无法接受抗凝治疗。所有患者均未出现缺血症状,但有1例患者后来被发现在所累及动脉供血区域存在无症状性梗死。
动脉夹层是脑血管造影术和脑血管介入治疗罕见的并发症,通常临床病程良性。