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[颅内压升高和缺血性心脏病患者麻醉诱导后出现病态窦房结综合征(SSS)]

[Sick sinus syndrome (SSS) after induction of anesthesia in a patient with increased intracranial pressure and ischemic heart disease].

作者信息

Takayama K, Takahata O, Sengoku K, Fujimoto K, Iwasaki H

机构信息

Department of Anesthesiology and Critical Care Medicine, Asahikawa Medical College.

出版信息

Masui. 2000 Mar;49(3):289-91.

Abstract

An 84-year-old male with increased intracranial pressure (ICP) and ischemic heart disease was scheduled to undergo brain tumor resection. After induction of anesthesia using midazolam, fentanyl and vecuronium, sinus bradycardia, junctional rhythm and escape-capture bigeminy were observed. In spite of intravenous administration of lidocaine and atropine, the bigeminy did not disappear. As he awoke from anesthesia, his cardiac rhythm changed from a bigeminal to a regular sinus rhythm. After extubation, sinus arrest, which continued for up to 4.8 seconds, appeared frequently. A temporary pacing catheter was inserted and ventricular pacing was started (mode VVI rate 50 min-1). Four days later, the patient was again scheduled to undergo brain tumor resection. After induction of anesthesia with the same drugs as used before, his cardiac rhythm gradually became bradycardic, and a complete pacing rhythm was observed throughout the surgical procedure. After the operation had been completed, his cardiac rhythm changed to a regular sinus rhythm. In addition to degenerative and ischemic changes in the SA node, an increase in ICP secondary to a brain tumor is thought to have induced sick sinus syndrome after the induction of anesthesia.

摘要

一名84岁男性,患有颅内压(ICP)升高和缺血性心脏病,计划接受脑肿瘤切除术。使用咪达唑仑、芬太尼和维库溴铵诱导麻醉后,观察到窦性心动过缓、交界性心律和逸搏-夺获二联律。尽管静脉注射了利多卡因和阿托品,二联律仍未消失。当他从麻醉中苏醒时,心律从二联律转变为正常窦性心律。拔管后,窦性停搏频繁出现,持续长达4.8秒。插入临时起搏导管并开始心室起搏(VVI模式,频率50次/分钟)。四天后,患者再次计划接受脑肿瘤切除术。使用与之前相同的药物诱导麻醉后,他的心律逐渐变得缓慢,并且在整个手术过程中观察到完全起搏心律。手术完成后,他的心律转变为正常窦性心律。除了窦房结的退行性和缺血性改变外,脑肿瘤继发的颅内压升高被认为在麻醉诱导后诱发了病态窦房结综合征。

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