用于测定溴化丁基东莨菪碱的液膜离子选择电极

[Ion-selective electrodes with a liquid membrane for determining N-butylscopolammonium bromide].

作者信息

Bibire N, Dorneanu V

机构信息

Disciplina de Chimie Analitică, Facultatea de Farmacie, Universitatea de Medicină şi Farmacie Gr. T. Popa, Iaşi.

出版信息

Rev Med Chir Soc Med Nat Iasi. 1999 Jan-Jun;103(1-2):190-4.

PMID:10756910

Abstract

Two ion-selective electrodes with liquid membrane for N-butylscopolamonium bromide are described, with N-butylscopolamonium tetraphenylborate (I) and N-butylscopolamonium reineckate (II), respectively, solved in benzylic alcohol as electroactive material. These electrodes have a linear response in the concentration range of 10(-2)-10(-6) M N-butylscopolamonium bromide, with the detection limit of 10(-7) M for both electrodes. These electrodes were used with good results for quantitative assay by direct potentiometry of injectable solutions of N-butylscopolamonium bromide.

摘要

本文描述了两种用于溴化N-丁基东莨菪碱的液膜离子选择电极，分别将四苯基硼酸N-丁基东莨菪碱（I）和雷氏盐N-丁基东莨菪碱（II）溶解在苄醇中作为电活性物质。这些电极在10（-2）-10（-6）M溴化N-丁基东莨菪碱浓度范围内呈线性响应，两个电极的检测限均为10（-7）M。这些电极用于溴化N-丁基东莨菪碱注射液的直接电位法定量测定，效果良好。