Ho V
John M. Olin School of Business, Washington University, St Louis, MO 63130-4899, USA.
Circulation. 2000 Apr 18;101(15):1806-11. doi: 10.1161/01.cir.101.15.1806.
Hospitals performing more surgical procedures tend to yield better outcomes. This study examines the evolution of this volume-outcome relation over time.
The relation between the number of percutaneous transluminal coronary angioplasty (PTCA) procedures performed at hospitals (volume) and in-hospital bypass surgery and death for 353 488 patients treated in California between 1984 and 1996 was examined. Descriptive statistics and logistic regression were used to compare outcomes for 3 periods: 1984 to 1987, 1988 to 1992, and 1993 to 1996. The in-hospital mortality rate was 2.5% for hospitals performing <200 PTCA procedures per year but only 1.3% for hospitals performing >400 procedures per year in 1984 to 1987. By 1993 to 1996, mortality rates in these 2 volume categories narrowed to 1.7% and 1.3%, respectively. Bypass surgery rates also narrowed and fell in low-volume (<200 procedures) versus high-volume (>400 procedures) hospitals from 12.4% versus 6.9% in 1984 to 1987 to 4.6% versus 3.3% in 1993 to 1996. In a logistic regression, PTCA procedures significantly predicted in-hospital mortality and bypass surgery rates in all 3 time periods. However, coefficient estimates indicate that improvements over time in outcomes for hospitals performing <200 procedures were comparable to the predicted benefits of increasing volume above 400 procedures within time periods.
Over time, the disparity in outcomes between low- and high-volume hospitals has narrowed, and outcomes have improved significantly for all hospitals. Given these improvements, lower minimum volume standards may be advisable in less populated areas, where the alternative is no angioplasty at all.
进行更多外科手术的医院往往能取得更好的治疗效果。本研究探讨了这种手术量与治疗效果之间的关系随时间的演变情况。
研究了1984年至1996年期间加利福尼亚州353488例接受经皮腔内冠状动脉成形术(PTCA)治疗的患者,分析了医院进行PTCA手术的数量(手术量)与住院期间旁路手术及死亡情况之间的关系。采用描述性统计和逻辑回归方法对三个时间段(1984年至1987年、1988年至1992年、1993年至1996年)的治疗效果进行比较。1984年至1987年,每年进行PTCA手术少于200例的医院,其住院死亡率为2.5%,而每年进行PTCA手术超过400例的医院,住院死亡率仅为1.3%。到1993年至1996年,这两类手术量医院的死亡率分别降至1.7%和1.3%。低手术量(<200例手术)医院与高手术量(>400例手术)医院的旁路手术率差距也缩小且降低,从1984年至1987年的12.4%对6.9%降至1993年至1996年的4.6%对3.3%。在逻辑回归分析中,PTCA手术数量在所有三个时间段均能显著预测住院死亡率和旁路手术率。然而,系数估计表明,在各时间段内,每年进行手术少于200例的医院治疗效果的改善程度与手术量增加到400例以上所预测的益处相当。
随着时间推移,低手术量医院和高手术量医院之间的治疗效果差距已缩小,所有医院的治疗效果均有显著改善。鉴于这些改善情况,在人口较少的地区,建议采用较低的最低手术量标准,因为否则就根本无法进行血管成形术。