Anadol D, Kiper N, Göçmen A, Ozçelik U
Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara.
Turk J Pediatr. 1999 Jan-Mar;41(1):53-9.
Miliary tuberculosis is a severe manifestation of tuberculosis. Six children aged between two months and 10 years with the diagnosis of miliary tuberculosis were treated with intermittent antituberculous therapy for six, nine or 12 months. All the patients showed clearance of both clinical and radiological symptoms; there was no drug toxicity or resistance and no relapses were seen in the follow-up period ranging from nine months to nine years. Intermittent therapy is safe and effective in miliary tuberculosis and it may be an alternative therapy because of its minimal toxicity and lower cost.
粟粒性肺结核是结核病的一种严重表现形式。6名年龄在2个月至10岁之间、被诊断为粟粒性肺结核的儿童接受了为期6个月、9个月或12个月的间歇性抗结核治疗。所有患者的临床和放射学症状均消失;未出现药物毒性或耐药性,在9个月至9年的随访期内未见复发。间歇性治疗在粟粒性肺结核中是安全有效的,因其毒性极小且成本较低,可能是一种替代疗法。