Dickman R, Shaklai M, Lapidot M, Okon E, Zandbank J, Fraser G M, Niv Y
Department of Gastroenterology, Rabin Medical Center, Sackler School of Medicine, Tel Aviv University, Israel.
J Clin Gastroenterol. 2000 Apr;30(3):299-302. doi: 10.1097/00004836-200004000-00019.
The association between gastric carcinoid tumors and pernicious anemia is well recognized. Such tumors occur in the presence of achlorhydria, chronic atrophic gastritis, hypergastrinemia, and enterochromaffin-like cell hyperplasia. In this case report, a 29-year-old woman with pernicious anemia and autoimmune thrombocytopenia who developed gastric carcinoid tumors of the gastric body is described. This is the second description of pernicious anemia associated with autoimmune thrombocytopenia. This association in a young woman together with the therapeutic options and decisions that were taken in the treatment of the patient are discussed.
胃类癌肿瘤与恶性贫血之间的关联已得到充分认识。此类肿瘤在胃酸缺乏、慢性萎缩性胃炎、高胃泌素血症和肠嗜铬样细胞增生的情况下发生。在本病例报告中,描述了一名患有恶性贫血和自身免疫性血小板减少症并发生胃体部胃类癌肿瘤的29岁女性。这是第二例关于恶性贫血合并自身免疫性血小板减少症的描述。本文讨论了在一名年轻女性中出现的这种关联以及针对该患者所采取的治疗选择和决策。