Gagnebin J, Jaques B, Pasche P
Service d'ORL et de chirurgie cervico-faciale, Centre Hospitalier Universitaire Vaudois, Lausanne.
Schweiz Med Wochenschr Suppl. 2000;116:39S-42S.
The purpose of this retrospective study was to evaluate oncological and functional results after reconstruction of the anterior floor of the mouth using free flaps.
From 1992 to 1998, 30 patients with squamous cell carcinoma of the anterior floor of the mouth underwent surgical excision and primary reconstruction with either free forearm- or bone-composed flaps. Functional assessment included evaluation by the Karnofsky scale, Performance Status Scale for Head and Neck Cancer (PSS-HNC), articulation test and videofluoroscopic examination.
16 patients underwent reconstruction with a free forearm flap, 13 with an iliac crest flap and 1 with a fibula flap. The most serious local complication was partial flap necrosis in two cases. Local control was 90% at 24 months and the specific survival rate was 92% at five years. Functional evaluation was performed on 19 patients: PSS-HNC median score for diet was 70 (range 50-100), the score for speech was 70 (range 50-100) and the score for "eating in public" was 65 (range 25-100). Patients with a major mobile tongue resection had a lower score compared to patients with minor or no mobile tongue resection. Videofluoroscopy showed swallowing alterations following large resections of soft tissues.
Our study confirms that wide resection of mobile tongue is associated decreased rehabilitation quality. Mandibulectomy does not influence rehabilitation.
本回顾性研究的目的是评估使用游离皮瓣重建口腔前底部后的肿瘤学和功能结果。
1992年至1998年,30例口腔前底部鳞状细胞癌患者接受了手术切除,并使用游离前臂皮瓣或骨组合皮瓣进行一期重建。功能评估包括通过卡诺夫斯基量表、头颈癌性能状态量表(PSS-HNC)、发音测试和电视荧光镜检查进行评估。
16例患者接受了游离前臂皮瓣重建,13例接受了髂嵴皮瓣重建,1例接受了腓骨皮瓣重建。最严重的局部并发症是2例皮瓣部分坏死。24个月时局部控制率为90%,5年时特异性生存率为92%。对19例患者进行了功能评估:PSS-HNC饮食中位数评分为70(范围50-100),言语评分为70(范围50-100),“在公共场合进食”评分为65(范围25-100)。与进行小范围或未进行活动舌部切除的患者相比,进行大范围活动舌部切除的患者评分较低。电视荧光镜检查显示在软组织大范围切除后吞咽有改变。
我们的研究证实,大范围活动舌部切除与康复质量下降有关。下颌骨切除术不影响康复。