Koyanagi I, Iwasaki Y, Hida K, Abe H, Isu T, Akino M, Aida T
Hokkaido Neurosurgical Memorial Hospital, Sapporo, Japan.
Childs Nerv Syst. 2000 Mar;16(3):143-9. doi: 10.1007/s003810050481.
The purpose of this study was to determine factors that might be involved in neurological deterioration and the role of surgical treatment in patients with lumbosacral spinal lipoma. Pre- and postoperative courses of 34 patients were retrospectively analyzed. The age at surgery ranged from 1 month to 47 years. The records of preoperative neurological status indicated that older patients had more severe deficits, while all 8 asymptomatic patients were under 5 years of age. Motor deficits were noted in 9 patients, in 7 of whom the lipoma extended cranially beyond the L5 level. Transitional-type lipomas were accompanied by more severe deficits (asymptomatic 1, symptomatic 17) than other types (asymptomatic 7, symptomatic 9). Postoperative follow-up periods ranged from 5 months to 13 years. During these periods, 7 of the 8 asymptomatic patients remained neurologically intact. Nine of the 26 symptomatic patients improved. Age, extension of the lipoma in the spinal canal and type of lipoma will influence the preoperative neurological status of the patients. Early untethering surgery is recommended in patients with large lipomas extending beyond the L5 level.
本研究的目的是确定可能与腰骶部脊髓脂肪瘤患者神经功能恶化相关的因素以及手术治疗的作用。对34例患者的术前和术后病程进行了回顾性分析。手术年龄从1个月至47岁不等。术前神经状态记录表明,年龄较大的患者神经功能缺损更严重,而所有8例无症状患者均在5岁以下。9例患者存在运动功能缺损,其中7例脂肪瘤向头侧延伸超过L5水平。过渡型脂肪瘤比其他类型(无症状7例,有症状9例)伴有更严重的神经功能缺损(无症状1例,有症状17例)。术后随访时间从5个月至13年不等。在此期间,8例无症状患者中有7例神经功能保持完好。26例有症状患者中有9例病情改善。年龄、脂肪瘤在椎管内的延伸范围以及脂肪瘤类型会影响患者的术前神经状态。对于脂肪瘤延伸超过L5水平的患者,建议早期进行脊髓松解手术。