Wilson A B, Haegert D G, Coombs R R
Clin Exp Immunol. 1975 Oct;22(1):177-82.
Human T lymphocytes are known to adhere to sheep erythrocytes. This affinity reaction was found to be consistently increased following treatment of the sheep cells with papain. Reactions with treated erythrocytes were more stable and involved higher percentages of lymphocytes. Using a double marker system of papain-treated sheep erythrocytes together with Fc rosettes as a presumptive B-cell marker, there was an overlap population of only 1% lymphocytes. Sheep erythrocytes treated with papain therefore appear to remain specifically adherent to human T lymphocytes.
已知人类T淋巴细胞会黏附于绵羊红细胞。在用木瓜蛋白酶处理绵羊细胞后,发现这种亲和反应持续增强。与经处理的红细胞的反应更稳定,涉及的淋巴细胞百分比更高。使用木瓜蛋白酶处理的绵羊红细胞与作为推定B细胞标志物的Fc玫瑰花结的双标记系统,仅有1%的淋巴细胞存在重叠群体。因此,经木瓜蛋白酶处理的绵羊红细胞似乎仍能特异性地黏附于人类T淋巴细胞。