Ashizawa Y, Maruyama A, Shibuya M, Hariu K, Tanaka W, Tohyama Y, Yotsukura M, Satoh S, Shimizu H, Tomomasa H, Iizumi T, Umeda T
Department of Urology, Teikyo University School of Medicine.
Hinyokika Kiyo. 2000 Apr;46(4):287-9.
Down's syndrome is an inherited disorder caused by trisomy of chromosome 21. In patients with Down's syndrome, an increased risk of leukemia has been observed. Recently, the coincidence of testicular cancer with this syndrome has been also emphasized. We present a case of Down's syndrome associated with testicular seminoma. This is the 19th case of Down's syndrome associated with testicular tumor in Japan.
唐氏综合征是一种由21号染色体三体性引起的遗传性疾病。在唐氏综合征患者中,已观察到白血病风险增加。最近,也有人强调了这种综合征与睾丸癌的巧合。我们报告一例与睾丸精原细胞瘤相关的唐氏综合征病例。这是日本第19例与睾丸肿瘤相关的唐氏综合征病例。